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Author:

Zhang, Hu (Zhang, Hu.) | Hu, Ting (Hu, Ting.) | Li, Zhe (Li, Zhe.) | Sun, Zhonghua (Sun, Zhonghua.) | Jia, Kebin (Jia, Kebin.) | Feng, Jinchao (Feng, Jinchao.)

Indexed by:

CPCI-S EI Scopus

Abstract:

Cherenkov-Excited Luminescence Scanned Tomography (CELST) involves a system of coupled continuous wave-domain diffusion equations for modeling. The excitation field quantized by the Complex Cosine (CC) method effectively simulates the forward light process in these equations. However, when considering x-ray-induced Cherenkov light within biological tissue, the CC-based excitation field lacks precision, instead requires the use of stochastic Monte Carlo (MC) methods. To accurately describe the radiation-induced light transport in biological tissue and CELST image reconstruction, in this paper, we develop a MC-based method for CELST, named sheet Monte Carlo (sMC). Experiments show that the sMC field can achieve 11.47 on contrast-to-noise ratio (CNR) and 0.74 on Pearson correlation (PC), while 7.25 and 0.57 for the CC initialization field under 4% noise level. Furthermore, our results highlight that the proposed excitation field exhibits superior reconstruction performance, especially when dealing with low ratios of fluorescent targets.

Keyword:

Cherenkov-excited luminescence scanned imaging Monte Carlo simulation image reconstruction

Author Community:

  • [ 1 ] [Zhang, Hu]Beijing Univ Technol, Fac Informat Technol, Beijing Key Lab Computat Intelligence & Intellige, Beijing 100124, Peoples R China
  • [ 2 ] [Hu, Ting]Beijing Univ Technol, Fac Informat Technol, Beijing Key Lab Computat Intelligence & Intellige, Beijing 100124, Peoples R China
  • [ 3 ] [Li, Zhe]Beijing Univ Technol, Fac Informat Technol, Beijing Key Lab Computat Intelligence & Intellige, Beijing 100124, Peoples R China
  • [ 4 ] [Sun, Zhonghua]Beijing Univ Technol, Fac Informat Technol, Beijing Key Lab Computat Intelligence & Intellige, Beijing 100124, Peoples R China
  • [ 5 ] [Jia, Kebin]Beijing Univ Technol, Fac Informat Technol, Beijing Key Lab Computat Intelligence & Intellige, Beijing 100124, Peoples R China
  • [ 6 ] [Feng, Jinchao]Beijing Univ Technol, Fac Informat Technol, Beijing Key Lab Computat Intelligence & Intellige, Beijing 100124, Peoples R China
  • [ 7 ] [Zhang, Hu]Beijing Lab Adv Informat Networks, Beijing 100124, Peoples R China
  • [ 8 ] [Hu, Ting]Beijing Lab Adv Informat Networks, Beijing 100124, Peoples R China
  • [ 9 ] [Li, Zhe]Beijing Lab Adv Informat Networks, Beijing 100124, Peoples R China
  • [ 10 ] [Sun, Zhonghua]Beijing Lab Adv Informat Networks, Beijing 100124, Peoples R China
  • [ 11 ] [Jia, Kebin]Beijing Lab Adv Informat Networks, Beijing 100124, Peoples R China
  • [ 12 ] [Feng, Jinchao]Beijing Lab Adv Informat Networks, Beijing 100124, Peoples R China

Reprint Author's Address:

  • [Zhang, Hu]Beijing Univ Technol, Fac Informat Technol, Beijing Key Lab Computat Intelligence & Intellige, Beijing 100124, Peoples R China;;[Zhang, Hu]Beijing Lab Adv Informat Networks, Beijing 100124, Peoples R China;;

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Source :

MOLECULAR-GUIDED SURGERY:MOLECULES, DEVICES, AND APPLICATIONS X

ISSN: 1605-7422

Year: 2024

Volume: 12825

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 8

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