The　NF1　gene　is　related　to　neurofibromatosis　type　1　(NF1),　which　is　an　autosomal　dominant　disorder　associated　with　multisystem　involvement　and　epilepsy　susceptibility.　A　human　induced　pluripotent　stem　cell　(iPSC)　line　was　derived　from　a　pediatric　patient　with　NF1　and　epilepsy,　harboring　a　heterozygous　NF1　gene　mutation.　The　iPSC　line　exhibits　high　levels　of　pluripotency　markers,　maintains　the　NF1　gene　mutation,　and　demonstrates　the　capacity　to　undergo　differentiation　potential　in　vitro　into　three　germ　layers.　The　iPSC　line　will　serve　as　a　valuable　resource　for　investigating　the　underlying　mechanisms　and　conducting　drug　screening　related　to　NF1　and　NF1-associated　epilepsy.　©　2024　The　Authors