With　the　development　of　intercity　high-speed　railways　towards　the　operation　mode　of　super　high　speed,　large　volume,　and　high　frequency,　the　viaduct　bears　more　and　more　dynamic　response,　which　is　bound　to　accelerate　the　accumulation　and　development　of　fatigue　damage　of　the　viaduct.　Therefore,　this　article　conducts　a　series　of　studies　on　the　fatigue　performance　of　box　girders,　ANSYS　finite　element　software　was　used　to　model　the　entire　fatigue　process　and　fatigue　reliability　analysis　of　the　test　beam,　and　a　fatigue　strength　verification　equation　for　the　inclined　section　of　prestressed　concrete　box　beams　was　established.　©　2024　selection　and　editorial　matter,　Seyed　Mohammadreza　Ghadiri　and　Yan　Zhuge:　individual　chapters,　the　contributors.　All　rights　reserved.