Background　To　control　resurging　infectious　diseases　like　mumps,　it　is　necessary　to　resort　to　effective　control　and　preventive　measures.　These　measures　include　increasing　vaccine　coverage,　providing　the　community　with　advice　on　how　to　reduce　exposure,　and　closing　schools.　To　justify　such　intervention,　it　is　important　to　understand　how　well　each　of　these　measures　helps　to　limit　transmission.Methods　In　this　paper,　we　propose　a　simple　SEILR　(susceptible-exposed-symptomatically　infectious-asymptomatically　infectious-recovered)　model　by　using　a　novel　transmission　rate　function　to　incorporate　temperature,　humidity,　and　closing　school　factors.　This　new　transmission　rate　function　allows　us　to　verify　the　impact　of　each　factor　either　separately　or　combined.　Using　reported　mumps　cases　from　2004　to　2018　in　the　mainland　of　China,　we　perform　data　fitting　and　parameter　estimation　to　evaluate　the　basic　reproduction　number　R　0　\documentclass[12pt]{minimal}　\usepackage{amsmath}　\usepackage{wasysym}　\usepackage{amsfonts}　\usepackage{amssymb}　\usepackage{amsbsy}　\usepackage{mathrsfs}　\usepackage{upgreek}　\setlength{\oddsidemargin}{-69pt}　\begin{document}$${\mathfrak　R}_0$$\end{document}　.　As　a　wide　range　of　one-dose　measles,　mumps,　and　rubella　(MMR)　vaccine　programs　in　China　started　only　in　2008,　we　use　different　vaccination　proportions　for　the　first　Stage　I　period　(from　2004　to　2008)　and　the　second　Stage　II　period　(from　2009　to　2018).　This　allows　us　to　verify　the　importance　of　higher　vaccine　coverage　with　a　possible　second　dose　of　MMR　vaccine.Results　We　find　that　the　basic　reproduction　number　R　0　\documentclass[12pt]{minimal}　\usepackage{amsmath}　\usepackage{wasysym}　\usepackage{amsfonts}　\usepackage{amssymb}　\usepackage{amsbsy}　\usepackage{mathrsfs}　\usepackage{upgreek}　\setlength{\oddsidemargin}{-69pt}　\begin{document}$${\mathfrak　R}_0$$\end{document}　is　generally　between　1　and　3.　We　then　use　the　Akaike　Information　Criteria　to　assess　the　extent　to　which　each　of　the　three　factors　contributed　to　the　spread　of　mumps.　The　findings　suggest　that　the　impact　of　all　three　factors　is　substantial,　with　temperature　having　the　most　significant　impact,　followed　by　school　opening　and　closing,　and　finally　humidity.Conclusion　We　conclude　that　the　strategy　of　increasing　vaccine　coverage,　changing　micro-climate　(temperature　and　humidity),　and　closing　schools　can　greatly　reduce　mumps　transmission.