Permeability　changes　induced　by　earthquakes　have　been　studied　widely.　However,　basic　questions　still　remain:　what　are　the　spatial　differences　in　permeability　changes　induced　by　far-field　earthquakes?　Is　there　an　inevitable　relationship　between　seismic　energy　density,　epicenter　azimuth　and　permeability　change?　We　try　to　answer　the　above　questions　by　examining　records　of　11　years　of　groundwater　hydrographs　of　7　wells　in　the　North　China　plain　at　large　distance　from　the　epicenters　of　221　earthquakes　during　the　period　2008　similar　to　2018.　The　results　shows　permeability　changes　varied　between　the　different　wells,　with　the　permeability　variation　of　the　JN　well　most　sensitively　responding　to　seismic　events,　while　the　least　sensitive　wells　being　SH,　JZ　and　LK.　We　found　that　the　azimuths　of　seismic　waves　can　greatly　influence　the　changes　in　permeability,　i.e.　mainly　concentrated　between　25　and　295　degrees.　The　seismic　density　energy　(SDE)　value　larger　than　approximately　10(-9)　J/m(3)　is　likely　to　induce　a　change　in　permeability　in　the　NCP　aquifer　materials.　It　is　found　that　SDE　is　not　a　predictor　of　permeability　change　at　a　given　well,　by　calculating　the　seismic　energy　density　which　did　not　cause　permeability　change.　While　the　permeability　change　ratio　before　and　after　the　earthquake　can　be　considered　as　the　ability　of　permeability　respond　to　the　dynamic　stress　and　it　shows　a　weak　correlation　with　depth　of　aquifer.　Thus,　Factors　that　probably　affect　permeability　responses　changes　would　have　implications　for　crustal　geomechanics.