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Author:

Wang, Weiping (Wang, Weiping.) | Zhang, Shunqi (Zhang, Shunqi.) | Wang, Zhen (Wang, Zhen.) | Luo, Xiong (Luo, Xiong.) | Luan, Ping (Luan, Ping.) | Hramov, Alexander (Hramov, Alexander.) | Kurths, Juergen (Kurths, Juergen.) | He, Chang (He, Chang.) | Li, Jianwu (Li, Jianwu.)

Indexed by:

SCIE

Abstract:

Mild cognitive impairment (MCI) is highly likely to convert to Alzheimer's disease (AD). The main approach to identifying MCI is using a functional connection network (FCN). Traditional FCN is used to study the correlation between two brain regions, but it lacks deeper brain interaction information. Neuroscientists found the internal functional activity pattern in the human brain is characterized by sparse, modular, and overlapping structures, and the FCN is restricted by the brain structural connection network (SCN). They can improve the estimation accuracy of FCN. Therefore, this article first constructs low order FCN (LFCN) based on brain sparse, modular, and overlapping activity patterns. Then, new high-order FCN (HFCN) is proposed based on the restrictive relationship between SCN and FCN. To combine high robustness of LFCN with high sensitivity of HFCN, a new combination strategy of LFCN and HFCN is proposed. It integrates the idea of brain modular and overlapping with the restricted relationship between SCN and FCN. Finally, the experimental results show that in early MCI (EMCI) recognition the best classification performance is acquired with an accuracy of 91.42%, which is better than similar methods. This method will be instrumental in the early recognition of clinical MCI.

Keyword:

multimodal magnetic resonance imaging (MRI) mild cognitive impairment (MCI) early diagnosis Associated high-order functional connectivity network

Author Community:

  • [ 1 ] [Wang, Weiping]Univ Sci & Technol Beijing, Sch Comp & Commun Engn, Beijing, Peoples R China
  • [ 2 ] [Zhang, Shunqi]Univ Sci & Technol Beijing, Sch Comp & Commun Engn, Beijing, Peoples R China
  • [ 3 ] [Luo, Xiong]Univ Sci & Technol Beijing, Sch Comp & Commun Engn, Beijing, Peoples R China
  • [ 4 ] [He, Chang]Univ Sci & Technol Beijing, Sch Comp & Commun Engn, Beijing, Peoples R China
  • [ 5 ] [Wang, Weiping]Univ Sci & Technol Beijing, Beijing Key Lab Knowledge Engn Mat Sci, Beijing 100083, Peoples R China
  • [ 6 ] [Luo, Xiong]Univ Sci & Technol Beijing, Beijing Key Lab Knowledge Engn Mat Sci, Beijing 100083, Peoples R China
  • [ 7 ] [Wang, Weiping]Univ Sci & Technol Beijing, Shunde Grad Sch, Foshan 528399, Guangdong, Peoples R China
  • [ 8 ] [Luo, Xiong]Univ Sci & Technol Beijing, Shunde Grad Sch, Foshan 528399, Guangdong, Peoples R China
  • [ 9 ] [Wang, Zhen]Northwestern Polytech Univ, Sch Cyberspace, Xian 710072, Peoples R China
  • [ 10 ] [Wang, Zhen]Northwestern Polytech Univ, Sch Artificial Intelligence Opt & Elect, Xian 710072, Peoples R China
  • [ 11 ] [Luan, Ping]Shenzhen Univ, Guangdong Prov Gen Hosp 2, Shenzhen 518060, Peoples R China
  • [ 12 ] [Luan, Ping]Shenzhen Univ, Hlth Sci Ctr, Shenzhen 518060, Peoples R China
  • [ 13 ] [Hramov, Alexander]Innopolis Univ, Ctr Technol Robot & Mechatron Components, Innopolis 420500, Russia
  • [ 14 ] [Hramov, Alexander]Saratov State Med Univ, Inst Cardiol Res, Saratov 410012, Russia
  • [ 15 ] [Kurths, Juergen]Humboldt Univ, Inst Phys, D-10099 Berlin, Germany
  • [ 16 ] [Kurths, Juergen]Potsdam Inst Climate Impact Res, Res Dept Complex Sci, D-14473 Potsdam, Germany
  • [ 17 ] [Li, Jianwu]Beijing Univ Technol, Inst Frontier Technol, Jinan 250300, Peoples R China
  • [ 18 ] [Li, Jianwu]Huanghe Sci & Technol Coll, Dept Engn, Zhengzhou 450000, Peoples R China

Reprint Author's Address:

  • [Wang, Weiping]Univ Sci & Technol Beijing, Sch Comp & Commun Engn, Beijing, Peoples R China;;[Wang, Weiping]Univ Sci & Technol Beijing, Beijing Key Lab Knowledge Engn Mat Sci, Beijing 100083, Peoples R China;;[Wang, Zhen]Northwestern Polytech Univ, Sch Cyberspace, Xian 710072, Peoples R China;;[Wang, Zhen]Northwestern Polytech Univ, Sch Artificial Intelligence Opt & Elect, Xian 710072, Peoples R China;;

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Source :

IEEE TRANSACTIONS ON COGNITIVE AND DEVELOPMENTAL SYSTEMS

ISSN: 2379-8920

Year: 2024

Issue: 2

Volume: 16

Page: 618-627

Cited Count:

WoS CC Cited Count: 3

SCOPUS Cited Count: 3

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 3

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