The　present　work　evaluated　the　removal　performances　of　Ni2+,　Cd2+,　Sr2+,　Mn2+,　and　Fe3+　from　an　aqueous　solution　using　a　comparison　between　synthetic　clinoptilolite　(SCP)　and　natural　CP　(NCP).　Unlike　previous　demonstrations　that　treated　each　metal　ion　individually,　these　five　metal　ions　and　the　used　adsorbents　were　combined　in　a　single　treatment　and　explored　via　various　characterizations,　such　as　XRD　patterns,　SEM　images,　N2　sorption　isotherms,　ICP,　and　AAS　analysis.　The　results　revealed　that　the　capacities　of　SCP　at　pH　3.0-8.0　and　25-75　degrees　C　were　nearly　20　times　higher　than　those　of　NCP,　showing　2000,　1720,　1875,　1510,　and　22　mg　g-　1,　for　Ni2+,　Fe3+,　Cd2+,　Mn2+,　and　Sr2,　respectively.　The　reason　is　mostly　attributed　to　its　purity　and　perfect　crystal　lattice.　The　kinetic　behaviors　in　both　cases　indicated　that　the　pseudo-2nd-order　model　provided　a　better　description.　Their　adsorption　behaviors　exhibited　a　better　fit　with　the　Freundlich　models　on　the　removal　of　Ni2+,　Cd2+,　and　Mn2+,　the　Langmuir　equation　on　the　removal　of　Fe3+,　and　both　Freundlich　and　Langmuir　on　the　removal　of　Sr2+,　respectively.　The　thermodynamic　findings　indicated　that　the　SCP　was　used　to　be　faster,　more　spontaneous,　and　had　a　better　favorable　adsorption　performance　than　the　NCP.　Additionally,　five　times　recyclability　and　different　stability　tests　further　supported　the　dominant　adsorbent　nature　of　using　SCP　as　an　adsorbent.