A　parametric　model　for　the　tensile-shear　spot　welded　structure　of　ultra-high　strength　steel　was　established　with　software　ANSYS　by　APDL　to　analyze　the　static　strength　of　the　structure,　and　was　verified　with　experiments.　Based　on　the　simulated　results,　the　optimized　model　was　built　to　decrease　the　whole　materials,　and　some　sizes　of　the　structure　were　also　optimized.　The　response　surface　methodology　was　adopted　to　make　the　stress　constraints　explicit,　and　the　sequential　quadratic　programming　algorithm　was　used　to　achieve　the　most　suitable　solutions　of　the　optimized　model.　The　results　show　that　this　method　could　effectively　enhance　the　solving　efficiency　and　avoid　oscillation.　The　calculation　procedure　was　programmed　with　C　language　in　order　to　improve　efficiency,　and　the　results　indicate　that　the　optimization　was　feasible　and　effective.