The　leather　industry　has　contributed　significantly　to　economic　development,　but　serious　water　environmental　problems　have　arisen　due　to　manufacturing　processes　in　this　industry.　The　leather　industry　must　implement　sustainable　development　by　improving　cleaner　production　capabilities　under　the　Chinese　ecological　development　background.　The　Xinji　industrial　park　in　China　has　the　largest　leather　production　base　in　which　the　leather　industry　is　the　leading　industry　that　contributes　nearly　50%　of　economic　gains.　This　study　investigated　optimal　cleaner　production　strategies　for　the　leather　industrial　park　by　adopting　an　improved　multi-objective　simulation　approach　integrating　the　environmentally　extended　input-output　and　system　dynamics　models.　Simulations　were　able　to　estimate　the　socio-economic　and　water　environment　development　of　the　Xinji　industrial　park　from　2015　to　2025.　Adopting　cleaner　approaches,　including　production　efficiency　enhancing,　sewage　pre-treatment　facility　construction　in　leather　companies,　and　reclaimed　water　recycling,　simulation　results　indicated　that,　with　steady　economic　growth　(optimal　7.7%　annual　growth　rate),　it　is　possible　to　conserve　18%　of　the　water　resources,　with　an　80　%　and　90%　reduction　for　the　chemical　oxygen　demand　(COD),　ammonia　(NH3-N)　water　pollutant　emission　intensity,　respectively.　The　cleaner　development　path　and　measures　analyzed　in　this　study　are　of　great　significance　to　promote　the　sustainable　development　of　leather　industrial　parks.