Earthquakes　contain　complex　components　in　both　the　horizontal　and　vertical　directions.　However,　most　vibration　control　strategies　work　only　in　a　single　direction.　The　existing　multi-dimensional　isolation　devices　usually　have　complex　designs　and　low　damping　ratios;　hence,　the　stability　of　structures　that　incorporate　the　devices　is　currently　insufficient.　This　study　designs　a　novel　multi-dimensional　isolation　and　mitigation　device　based　on　viscoelastic　damping　technology　(VE-MDIMD).　The　device　consists　of　a　core　bearing　and　several　cylindrical　dampers,　providing　vibration　control　capacity　in　both　the　horizontal　and　vertical　directions　and　a　strong　uplift　resistance.　To　evaluate　the　device＇s　performance,　a　series　of　dynamic　tests　are　conducted　on　the　cylindrical　damper　utilized　in　the　device.　The　results　show　that　the　damper＇s　mechanical　properties　exhibit　a　pronounced　dependence　on　the　frequency　and　amplitude,　and　its　hysteresis　curves　become　obviously　nonlinear　with　increased　deformation.　Subsequently,　to　describe　the　behavior　of　the　VE-MDIMD,　a　mechanical　model　is　established　which　combines　the　construction　of　the　device　and　the　characteristics　of　the　damper.　Considering　the　limitations　of　existing　models　in　fully　capturing　the　nonlinear　behavior　of　the　damper,　a　novel　multi-scale　model　is　proposed　based　on　the　microstructure　of　viscoelastic　material.　The　experimental　verification　confirms　that　the　model　can　accurately　capture　the　frequency　and　amplitude　dependence,　as　well　as　the　nonlinear　hysteresis　behavior,　of　the　damper.　Finally,　the　effectiveness　of　the　VE-MDIMD　is　evaluated　through　the　dynamic　analysis　of　an　actual　structure.　The　arrangement　of　the　device　in　the　structure　is　optimized　based　on　a　multi-objective　genetic　algorithm　available　in　Matlab　(R2019b)　and　OpenSEES　(Version　3.0.0).　The　results　demonstrate　the　device＇s　superiority　in　controlling　both　horizontal　and　vertical　vibrations　in　the　superstructure.