Purpose　Vertebral　fat-water　changes　are　associated　with　osteoporosis　or　aging,　and　usually　the　changes　are　assessed　with　advanced　magnetic　resonance　imaging　(MRI)　techniques.　In　this　study,　routine　T1-　and　T2-weighted　sequences　are　employed　to　introduce　novel　MRI　scores　for　indicating　fat-water-like　changes.　Methods　A　retrospective　study　of　165　females　(42　+/-　13　years),　and　a　pilot　study　of　twenty　volunteers　(60.85　+/-　5.05)　examined　with　MRI,　were　conducted.　Mean　signal　intensities　(SIs)　were　calculated　for　926　vertebrae　(L1　-　L5).　F-score(sc.fat)　(for　fat)　and　W-score(cs.fluid)　(for　water)　were　defined　as　the　median　SI　from　L1　-　L5　over　subcutaneous　fat　(T1WI-control)　and　cerebrospinal　fluid　(T2WI-control),　respectively.　Reliability　analysis　was　conducted　to　evaluate　the　consistency　of　the　scores,　and　Pearson　correlation　was　used　to　assess　the　relationships　between　variables　and　age.　Unpaired　t-tests　were　employed　to　identify　differences　between　the　abnormal　and　control　groups,　with　significance　set　at　p　＜　0.05.　The　distribution　of　scores　was　examined　using　box-and-whisker　plots,　alongside　descriptive　statistics　for　both　the　scores　and　associated　diseases.　Results　Moderate-to-strong　positive　correlations　were　found　between　F-score(sc.fat)　(r　=　0.67,　p　＜　0.05)　and　W-score(cs.fluid)　(r　=　0.49,　p　＜　0.05)　vs.　patient　age,　compared　to　signal-to-noise　ratio　(SNR)　vs.　age　(T1WI,　r　=　0.18;　T2WI,　r　=　0.04).　Significantly,　higher　scores　were　reported　in　patients　with　spine　disorders.　The　F-score(sc.fat)　(5.77　and　4.36)　and　W-score(cs.fluid)　(6.67　and　5.13)　were　found　to　differentiate　between　volunteers　with　and　without　osteoporosis　(defined　by　the　DXA　T-score).　Conclusion　A　novel　MRI　scoring　method　was　introduced　indicating　fat-water-like　changes,　utilizing　routine　sequences.　The　scores　correlated　with　aging　and　can　distinguish　between　healthy　and　diseased　spines.