High-entropy　strategy　is　emerging　as　a　feasible　and　effective　way　for　designing　functional　ceramics　with　outstanding　piezoelectric　properties　via　disordering　composition　distribution　through　increasing　in　atomic　species.　However,　there　still　showing　a　huge　difference　in　piezoelectric　properties　of　different　systems　with　the　same　configuration　entropy　value　(Delta　S),　which　may　be　related　to　the　binding　type　of　chemical　bond　caused　by　different　element　species,　ionic　radius,　and　electronegativity,　etc.　Herein,　the　chemical　bonding　engineering　is　proposed　to　decipher　the　influence　mechanism　of　bond　heterogeneity　and　hybrid　inhomogeneity　on　the　properties　of　KNN-based　piezoelectric　materials　with　the　same　Delta　S.　The　results　indicated　that　a　larger　differences　in　bond　lengths　may　cause　larger　local　ferroelectric　distortion,　which　was　beneficial　to　maintain　the　lattice　asymmetry　and　result　in　an　increased　energy　barrier,　thus　improving　the　thermal　stability　of　piezoelectricity;　and　the　introduction　of　a　small　amount　of　weakly　hybridized　bonding　in　isentropic　ceramic　system　may　soften　the　local　short-range　repulsions　and　promote　the　off-centering　displacement　of　neighboring　Nb　to　hybridize　with　O,　leading　to　the　enhancement　of　the　overall　chemical　bond　and　bringing　outstanding　piezoelectric/dielectric　response.　Importantly,　the　cantilever　piezoelectric　energy　harvester　assembled　by　the　optimized　KNN-based　piezoceramic　displays　outstanding　temperature　stability　of　power　generation　(the　output　current　density　decreased　only　19.26　%　from　25　to　100　degrees　C)　and　anti-fatigue　properties　(stable　up　to　104　cycles).　Overall,　this　pivotal　strategy　provides　meaningful　insight　into　the　design　of　functional　ceramics　via　the　chemical　bonding　engineering.