The　slow　kinetics　of　the　oxygen　evolution　reaction　(OER)　has　limited　the　development　of　new　energy　technologies.　Transition-metal　spinel　oxides　have　become　efficient　catalysts　owing　to　their　outstanding　OER　catalytic　activities.　However,　their　activity　and　stability　can　be　low　owing　to　a　deficiency　of　active　sites,　which　needs　to　be　solved.　In　this　study,　rare-earth　element　doping　was　used　to　adjust　the　internal　charge　redistribution　strategy　of　spinel　to　significantly　improve　the　OER　performance.　Pr-doped　NiFe2O4　(Pr-NiFe2O4)　exhibits　an　overpotential　of　339　mV　at　a　current　density　of　10　mA　cm(-2).　In　situ　Raman　spectroscopy　and　density　functional　theory　calculations　indicate　that　this　is　attributed　to　the　simultaneous　activation　of　the　surface　active　centers　Fe-OOH　and　Ni-OOH　by　Pr　doping,　as　Pr　can　regulate　oxygen　vacancies　and　adsorbed　oxygen　on　the　surface　of　catalyst　and　improve　covalent　bonding　between　O　2p　and　metal　3d　orbitals.　Moreover,　surface　valence　state　analysis　and　dissolution　testing　proved　that　Pr　doping　inhibits　the　excessive　oxidation　and　dissolution　of　transition　metals　in　the　catalysts,　effectively　stabilizing　the　catalyst　after　100　h　of　CA　testing.　This　study　provides　a　new　approach　for　the　design　of　spinel　materials　with　high　OER　performances.