To　improve　the　reliability　of　macroscopic　road　network　evaluation,　this　paper　studies　road　network　rigional　division　methods,　proposes　the　traffic　grid　definition　of　road　network,　and　then　redefines　the　urban　road　network　by　taking　the　traffic　grids　as　basic　elements.　The　spatial　autocorrelation　theory-based　road　network　regional　division　method　is　proposed　by　analyzing　the　characteristics　of　road　network　operation.　This　modified　method　can　reflect　the　influence　between　adjacent　regional　units,　and　improve　the　reliability　of　road　network　regional　division.　Finally,　this　research　takes　Beijing　as　a　case,　and　divides　the　road　network　into　regional　units　based　on　multi-source　traffic　data.　Result　shows　that　it　is　useful　for　scientifically　describing　the　fluctuation　and　evolution　of　road　network　operation　status.