Expressions　of　miRNA　in　human　mesenchymal　stem　cells　derived　from　umbilical　cord　and　bone　marrow　were　detected　by　microarray.　Results　indicated　that　the　expressions　of　a　set　of　26　miRNA　were　different　in　UMSCs　and　BMSCs.　miR-29b,　miR-20a,　miR-31,　miR-20b　and　miR-106a　exhibited　higher　expressions　in　UMSCs,　and　fold　changes　were　higher　than　3.　However,　miR-138　demonstrated　lower　expression.　Based　on　this　study,　6　miRNAs　of　particular　interests　were　confirmed　by　real-time　PCR,　and　the　results　coincidented　with　those　of　mircoarray.　Target　genes　predictive　were　correlated　with　mRNA　transcript,　translation,　and　the　functions　of　cell　proliferation,　division,　and　signal　transduction.