This　paper　aims　to　evaluate　the　elastic　modulus　of　concrete　with　nanoidentation　technique　and　homogenization　method.　In　this　paper,　concrete　is　divided　into　two　parts:　coarse　pore　and　matrix.　It　is　assumed　that　matrix　is　composed　of　five　phases:　stone　aggregate,　ITZ-1　(interfacial　transition　zone　around　stone　aggregate),　sand,　ITZ-2　(interfacial　transition　zone　around　sand)　and　paste.　Based　on　the　Ca/Si　ratio　change　in　interface　region,　the　thicknesses　of　interfacial　transition　zone　around　stone　and　sand　were　determined,　respectively.　The　elastic　moduli　of　stone,　ITZ-1,　sand,　ITZ-2　and　paste　were　determined　by　nanoidentation　technique.　The　volume　fraction　of　each　phase　was　determined　by　Lu　&　Torquato　model.　The　elastic　modulus　of　matrix　was　calculated　by　Self-Consistent　Method.　Then,　combining　with　the　porosity　of　coarse　pore　determined　by　hardened　concrete　pore　structure　analyzer,　the　elastic　modulus　of　concrete　could　be　obtained　by　Mori-Tanaka　method.　Through　comparison,　it　is　found　that　the　error　between　the　theoretical　calculation　value　and　the　macroscopic　test　value　is　within　10%.　Therefore,　the　effectiveness　of　theoretical　prediction　model　proposed　in　this　paper　was　verified.　(C)　2019　Elsevier　Ltd.　All　rights　reserved.