The　hysteresis　loss　of　Ni-5　at.%W　(Ni5W)　substrate　contributes　considerably　to　the　alternating　current　(AC)　loss　of　coated　conductors　(CCs)　working　at　low　transporting　current　or　low-frequency　field.　In　the　present　work,　the　evolution　of　texture　and　magnetic　properties　in　Ni5W　substrates　is　analyzed　and　also　the　relationship　between　magnetic　properties　and　the　extrinsic　characteristics　(evolved　due　to　the　processing　techniques)　is　determined.　By　making　the　comparison,　we　discovered　the　magnetic　domain　structures　of　Ni5W　substrates　for　the　first　time,　achieving　a　strip/branched　domain　structures　in　the　recrystallized　substrates.　The　hysteresis　loss　has　been　decreased　dramatically　for　the　recrystallized　substrates.　Interestingly,　we　also　observed　that　this　loss　is　also　related　to　the　annealing　temperature　in　the　fully　recrystallized　substrates.　The　reduced　loss　can　be　mainly　attributed　toward　the　decrease　of　grain　boundary,　which　proves　the　contribution　of　grain　size　toward　the　reduction　of　hysteresis　loss.　This　result　provides　a　new　insight　to　tailor　the　hysteresis　loss　of　Ni5W　substrates　used　for　coated　conductors.