We　detected　the　expression　of　telomerase　in　NIH/3T3　cells　to　investigate　the　potential　adverse　effects　of　long-term　1800　MHz　electromagnetic　radiation　(EMR).　NIH/3T3　cells　were　intermittently　(5　min　on/10　min　off)　exposed　to　1800　MHz　radiation　at　an　average　specific　absorption　rate　(SAR)　of　2　W/kg　by　simulating　GSM　(Talk　mode).　The　telomerase　expression　was　detected　by　ELISA.　These　results　showed　that　the　telomerase　expression　in　group　exposed　for　60　days　had　no　significant　difference　compared　to　the　sham　group,　however,　its　expression　in　the　138　days　exposed　group　significantly　increased　(p　©　2015　Taylor　&　Francis　Group,　London.