In　this　study,　static　tests　were　conducted　using　high　algae-laden　simulated　water　sample　under　laboratory　conditions.　Microcystis　aeruginosa　biomass　was　characterized　by　Chlorophyll　a,　and　Microcystic　toxins　LR　was　detected　by　solid　phase　extraction-　high　performance　liquid　chromatography.　The　removal　effect　ofMicrocystis　aeruginosa　and　Microcystic　toxins　LR　of　Copper　sulfate,　Zeolite,　Potassium　Permanganate　and　Potassium　Permanganate　supported　zeolite(Mn-Zeolite)　algaecide　had　been　investigated.　The　results　showed　that　five　day　after　dosing,　copper　sulfate　and　Mn-Zeolite　had　the　optimal　removal　rate　over　80%　of　Chlorophyll　a.　Removal　rate　of　Chlorophyll　a　by　potassium　permanganate　reached　60%∼80%.　While　zeolite　was　the　least　effective　to　remove　Chlorophyll　a,　with　a　removal　rate　of　only　30%　Zeolite　alone　and　Mn-Zeolite　both　had　an　effective　removal　rate　of　MC-LR,　over　50%.　MC-LR　could　be　removed　by　30%　after　dosing　0.09mg/L　of　potassium　permanganate,　but　MC-LR　in　water　increased　to　different　extent　when　the　dosage　of　potassium　permanganate　increased.　As　to　copper　sulfate,　MC-LR　in　water　all　increased　sharply　under　different　dosages.　Potassium　Permanganate　supported　zeolite(Mn-Zeolite)　algaecide　had　an　optimal　removal　effect　not　only　of　Microcystis　aeruginosa　but　also　of　Microcystic　toxins　compared　to　other　three　algaecides.　©　2011　IEEE.