With　the　advance　of　semiconductor　technology　and　the　development　of　multimedia　techniques,　CMOS　image　sensor　is　extensively　applied　in　medical　and　other　industrial　areas.　Integrator　array　is　the　front-end　processing　circuit　of　CMOS　image　sensor,　whose　performance　directly　determines　the　image　quality　generated　by　image　sensor.　Currently,　integrator　array　has　become　one　research　hot　spot.　The　main　works　of　this　paper　are　focused　on　the　low　noise　image　sensor　design　and　implement.　The　test　results　show　that　the　expected　performance　of　the　chip　can　be　fulfilled.　©2010　IEEE.