3D　laser　processing　of　automobile　panel　in　new　car　trial-manufacture　has　obvious　advantages:　it　can　replace　some　trimming　and　drilling　dies,　reduce　the　number　of　dies,　and　be　convenient　for　automobile　panel　changes.　We　use　self-developed　high-power　Nd:YAG　laser　processing　system　to　achieve　3D　trimming,　drilling　and　welding　of　automobile　panel.　Nd:YAG　laser　use　four-rods　resonator　structure　by　krypton　lamp-pumped,　the　output　power　is　200-2000W,　instability　is　less　than　2%,　the　laser　is　transmitted　by　fiber,　laser　processing　head　and　industrial　robot　make　up　of　laser　processing　system.　In　processing,　the　laser　output　power　are　controlled　by　system　control　panel,　and　the　robot　controls　processing　process,　include　path　of　processing,　laser　output,　processing　speed,　opening　and　closing　of　processing　gas.　The　system　realizes　automatic　control.　The　system　meets　the　processing　requirements　of　automobile　panel,　and　easy　to　operate.