To　simulate　penicillin　fermentation　biomass　growth　process,　a　penicillin　batch　fermentation　biomass　growth　model　using　cellular　automata　is　established.　The　model　uses　three-dimensional　cellular　automata　as　its　growth　space,　and　uses　Morre　type　neighborhood　as　its　cell　neighborhood.　The　transition　rules　of　the　model　are　made　based　on　the　mechanism　and　dynamic　differential　equation　model　of　a　penicillin　batch　fermentation　process.　Each　cell　of　the　model　represents　a　single　or　specific　number　of　penicillin　production　bacteria,　and　has　various　states.　The　results　of　simulation　experiments　show　that　the　model　replicates　the　penicillin　batch　fermentation　biomass　growth　process　described　by　a　dynamic　differential　equation　model　accordantly.　The　establishment　of　this　model　makes　it　possible　to　model,　simulate　and　control　penicillin　fermentation　process　using　cellular　automata.