As　the　spreading　of　AIDS　over　the　world,　to　research　effective　anti-HIV　drugs　is　required.　The　review　contains　the　process　of　discovering　targets　for　anti-HIV　especially　entry/infuse,　reverse　transcriptase,　protease　and　integrase,　and　describes　the　effective　component　of　traditional　Chinese　drugs　for　these　targets　and　the　anti-HIV　drugs　being　researched　or　used　in　clinic.