To　enhance　the　sulfate　reduction　efficiency,　the　effects　of　temperature,　influent　pH,　HRT,　ρ(COD)/ρ(SO42-)　and　reflux　ratio　on　the　sulfate　reduction　were　discussed　by　using　small　space　anaerobic　moving　bed　biofilm　reactor.　Then　the　reducing　SO42-　efficiency　and　stable　operation　were　also　studied　under　high　load　conditions.　Results　indicate　that　the　optimal　conditions　for　reactor　operation　is　at　temperature　35℃,　influent　pH=7.0,　ρ(COD)/ρ(SO42-)=2.5,　HRT=8　h　and　reflux　ratio=4:1.　When　the　sulfate　reduction　rate　remains　in　the　range　of　78.77%-88.89%　and　sulfate　concentrations　ranges　from　1500　to　2500　mg/L;　sulfate　removal　rate　is　up　to　5.90　kg/m3·d　and　there　is　a　high　SO42-　reduction　capacity　in　reactor.　When　the　condition　of　the　influent　sulfate　concentrations　is　2250　mg/L　and　continuous　reactor　operation　for　20　d,　the　sulfate　removal　efficiency　reaches　more　than　87.13%　and　the　reactor　keeps　stable　operation.　©　2016,　Editorial　Department　of　Journal　of　Beijing　University　of　Technology.　All　right　reserved.