Palladium-based　catalysts　are　highly　active　for　eliminating　volatile　organic　compounds.　Reducing　the　use　of　noble　metals　and　enhancing　performance　of　a　catalyst　are　always　desirable.　The　three-dimensionally　ordered　macroporous　(3DOM)　Mn2O3-supported　transition　metal　M　(M=Mn,　Cr,　Fe,　and　Co)-doped　Au-Pd　nanoparticles　(NPs)　with　an　Au-Pd-xM　loading　of　1.86-1.97　wt%　were　prepared　using　the　modified　polyvinyl　alcohol-protected　reduction　method.　It　is　found　that　the　Au-Pd-xM　NPs　with　a　size　of　3.6-4.4nm　were　highly　dispersed　on　the　surface　of　3DOM　Mn2O3.　The　1.94wt%　Au-Pd-0.21Co/3DOM　Mn2O3　and　1.94wt%　Au-Pd-0.22Fe/3DOM　Mn2O3　samples　performed　the　best　for　the　oxidation　of　methane　and　o-xylene,　respectively.　The　methane　oxidation　rate　at　340　degrees　C　(339.0　x　10(-6)　mol/(g(pd)　s))　over　1.94wt%　Au-Pd-0.21Co/3DOM　Mn2O3　was　three　times　higher　than　that　(93.8　x　10-6　mol/(gpd　s))　over　1.97　wt%　Au-Pd/3DOM　Mn2O3,　and　the　o-xylene　reaction　rate　at　140　degrees　C　(2.59　mu　mol/(g(N)　s)　over　1.94wt%　Au-Pd-0.22Fe/3DOM　Mn2O3　was　two　times　higher　than　that　(0.93　mu　mol/(g(N)　s)　over　1.97　wt%　Au-Pd/3DOM　Mn2O3.　It　is　concluded　that　doping　a　certain　amount　of　the　transition　metal　to　Au-Pd/3　DOM　Mn2O3　could　modify　the　microstructure　of　the　alloy　NPs,　thus　improving　the　oxygen　activation　and　methane　adsorption　ability.　We　are　sure　that　the　M-doped　Au-Pd/3DOM　Mn2O3　materials　are　promising　catalysts　for　the　efficient　removal　of　volatile　organic　compounds.　(C)　2017　Elsevier　B.V.　All　rights　reserved.