Adobe　structure　of　rural　building　is　still　used　in　many　areas.　In　order　to　improve　its　seismic　performance,　a　kind　of　masonry　structure　composed　of　regeneration　brick　and　adobe,　as　well　as　glass　beads　-　graphite　foundation　seismic　isolation　was　proposed　to　reduce　the　seismic　response.　This　full　scale　composite　masonry　building　adopting　the　glass　beads　-　graphite　base　isolation　system　was　tested　on　a　shake　table.　Based　on　the　test,　the　structural　dynamic　behavior　and　damage　evolvement　process　were　studied.　Main　factors　influencing　the　structural　seismic　response　were　analyzed,　and　the　function　of　the　isolation　system　to　reduce　the　structural　seismic　response　was　clarified.　The　test　shows　that,　the　proposed　masonry　structure,　composed　of　regeneration　brick　and　adobe,　with　base　isolation　system,　has　good　performance;　under　small　earthquakes,　the　glass　beads　-　graphite　base　isolation　system　is　not　activated,　and　the　structural　seismic　response　similar　to　seismic　resistant　structures;　under　moderate　earthquakes,　the　base　isolation　system　starts,　and　the　seismic　effect　exerted　to　the　upper　structure　is　reduced;　under　major　earthquakes,　the　base　isolation　system　works　well,　which　effectively　mitigates　the　damage　of　the　upper　structure.　The　masonry　structures　composed　of　regeneration　brick　and　adobe　are　suitable　to　apply　in　rural　areas.