Query：
学者姓名：鲁理平
Refining：
Year
Type
Indexed by
Source
Complex
Co-Author
Language
Clean All
Abstract ：
A polymethionine (p-Met)-modified laser-induced graphene (LIG) electrode (p-Met/LIG) was constructed and integrated with a portable electrochemical workstation and handheld computer application to achieve simultaneous on-site detection of environmental water bodies. Among the azo dyes are sunset yellow (SY) and tartrazine (Tz). The laser processing parameters were optimized to prepare a sensing interface with the best conductive properties; Met was electropolymerized on the LIG surface to improve the electrochemical response of SY and Tz; by combining p-Met/LIG portable electrochemical sensors and small electrochemical workstations Integrated with a handheld computer application, a portable electrochemical sensing platform was built for detecting SY and Tz. Differential pulse voltammetry (DPV) was used to measure the two dyes, and the linear range of detecting SY was0.2-20 mu mol/Land 20-100 mu mol/L. The detection limit is as low as0.001 mu mol/L; The linear range of detecting Tz is0.3-40 mu mol/L and40-100 mu mol/L. The detection limit is0.005 mu mol/L.p-Met/LIG has excellent anti-interference performance, stability and reproducibility. This portable sensing platform was used for actual water sample detection, and the results showed that this platform is suitable for real-time on-site detection of SY and Tz in actual environmental water bodies
Keyword ：
Portable Portable Electrochemical sensor Electrochemical sensor Sunset yellow Sunset yellow Azo dye Azo dye Tartrazine Tartrazine Laser induced graphene Laser induced graphene
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Chang, Xue-Qing , Wang, Zi-Qi , Lu, Li-Ping . Portable electrochemical sensing platform for sensitive detection of azo dyes sunset yellow and tartrazine [J]. | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY , 2024 , 52 (1) : 62-71 . |
| MLA | Chang, Xue-Qing 等. "Portable electrochemical sensing platform for sensitive detection of azo dyes sunset yellow and tartrazine" . | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 52 . 1 (2024) : 62-71 . |
| APA | Chang, Xue-Qing , Wang, Zi-Qi , Lu, Li-Ping . Portable electrochemical sensing platform for sensitive detection of azo dyes sunset yellow and tartrazine . | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY , 2024 , 52 (1) , 62-71 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
The human telomeric DNA 3 ' single-stranded overhang comprises tandem repeats of the sequence d(TTAGGG), which can fold into the stable secondary structure G-quadruplex (G4) and is susceptible to oxidative damage due to the enrichment of G bases. 8-Oxoguanine (8-oxoG) formed in telomeric DNA destabilizes G4 secondary structures and then inhibits telomere functions such as the binding of G4 proteins and the regulation of the length of telomeres. In this work, we developed a G4-DNA self-assembled monolayer electrochemical sensing interface using copper-free click chemistry based on the reaction of dibenzocyclooctyl with azide, resulting in a high yield of DNA tethers with order and homogeneity surfaces, that is more suitable for G-quadruplex DNA charge transport (CT) research. At high DNA coverage density surfaces, G-quadruplex DNA is 4 times more conductive than double-stranded DNA owing to the well-stacked aromatic rings of G-quartets acting as good charge transfer channels. The effect of telomeric oxidative damage on G-quadruplex-mediated CT is investigated. The accommodation of 8-oxoG at G sites originally in the syn or anti conformation around the glycosyl bond in the nonsubstituted hTel G-quadruplex causes structural perturbation and a conformational shift, which disrupts the pi-stack, affecting the charge transfer and attenuating the electrochemical signal. The current intensity was found to correlate with the amount of 8-oxodG, and the detection limit was estimated to be approximately one lesion in 286 DNA bases, which can be converted into 64.7 fmol on the basis of the total surface DNA coverage. The improved G4-DNA order and homogeneity sensing interface represent a major step forward in this regard, providing a reliable and controlled electrochemical platform for the accurate measurement and diagnosis of G4-DNA oxidative damage.
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | He, Zhangjin , Wu, Jiening , Li, Wei et al. Investigation of G-Quadruplex DNA-Mediated Charge Transport for Exploring DNA Oxidative Damage in Telomeres [J]. | LANGMUIR , 2024 , 40 (36) : 18950-18960 . |
| MLA | He, Zhangjin et al. "Investigation of G-Quadruplex DNA-Mediated Charge Transport for Exploring DNA Oxidative Damage in Telomeres" . | LANGMUIR 40 . 36 (2024) : 18950-18960 . |
| APA | He, Zhangjin , Wu, Jiening , Li, Wei , Du, Yuying , Lu, Liping . Investigation of G-Quadruplex DNA-Mediated Charge Transport for Exploring DNA Oxidative Damage in Telomeres . | LANGMUIR , 2024 , 40 (36) , 18950-18960 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
利用核壳型的CdSe@CdS量子点作为发光物质，并用壳聚糖（CS）、类石墨烯氮化碳（gC_3N_4）与CdSe@CdS量子点合成了CdSe@CdS/CS/gC_3N_4复合物，将该复合物修饰至玻碳电极（GCE）表面，将适配体（Apt）的互补DNA链（cDNA）通过化学反应连接到量子点上，Apt与cDNA发生杂交反应而被修饰至电极表面。将辣根过氧化物酶（HRP）固定到该修饰电极表面，构建了检测卡那霉素（Kana）的电化学发光（ECL）适配体传感器。通过生物催化沉淀（BCP）方法实现Kana的检测，溶液中无Kana时，在H_2O_2的存在下，修饰在电极上的HRP可以催化氧化4-氯-1-萘酚（4-CN），在电极表面产生不导电的苯并-4-氯己二烯酮沉淀，导致电化学发光信号明显降低。溶液中存在Kana时，Kana会与Apt特异性结合，部分dsDNA解旋，导致部分HRP从电极表面脱落，BCP反应减弱，导致ECL信号增强，实现目标物质的特异性检测。计算适配体传感器在Kana溶液中的ECL强度（I）与传感器在空白溶液中的ECL强度（I_0）的差值ΔI (I-I_0)，并以此作为响应信号。结果显示，ΔI与Kana浓度的对数值在1.0×10~(-8)～1.0×10~(-4) g/L范围呈良好的线性关系，检出限为5 ng/L。该传感器在实际样品测定中具有较好的应用前景。
Keyword ：
电化学发光 电化学发光 卡那霉素 卡那霉素 量子点 量子点 适配体 适配体 生物催化沉淀 生物催化沉淀
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | 高会莲 , 康天放 , 鲁理平 et al. 基于CdSe@CdS/壳聚糖/gC_3N_4复合物的卡那霉素电化学发光适配体传感器 [J]. | 分析试验室 , 2023 , 42 (03) : 305-311 . |
| MLA | 高会莲 et al. "基于CdSe@CdS/壳聚糖/gC_3N_4复合物的卡那霉素电化学发光适配体传感器" . | 分析试验室 42 . 03 (2023) : 305-311 . |
| APA | 高会莲 , 康天放 , 鲁理平 , 程水源 . 基于CdSe@CdS/壳聚糖/gC_3N_4复合物的卡那霉素电化学发光适配体传感器 . | 分析试验室 , 2023 , 42 (03) , 305-311 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
Cadmium (Cd) can cause cell oxidative stress and cytotoxicity. Few studies have focused on inhibitory effects on Cd2+-induced oxidative stress and related cytotoxicity. Scanning electrochemical microscopy (SECM) is a highly sensitive and non-invasive electrochemical analytical method. However, no information exists on inhibitory effects on Cd2+-induced cell oxidative stress using SECM technology. Herein, we studied the effects of ascorbic acid (AsA), zinc chloride (ZnCl2), and calcium chelator 1,2-bis (2-aminophenoxy) ethane-N,N,N ',N '-tetraacetic acid tetraethoxy methyl ester (BAPTA-AM) on cell oxidative stress with SECM. Subsequently, we studied the inhibitory effects of AsA, ZnCl2, and BAPTA-AM on Cd2+-induced cell oxidative stress. Consequently, 50 mu mol L-1 AsA, 5 mu mol L-1 ZnCl2, and 5 mu mol L-1 BAPTA-AM did not produce reactive oxygen species (ROS) and had little effect on cell viability. However, they could significantly reduce Cd2+-induced excessive ROS and alleviate apoptosis (P < 0.01). Additionally, AsA had the strongest inhibitory effects on Cd2+-induced oxidative stress, followed by BAPTA-AM and ZnCl2. The inhibitory effects of AsA, ZnCl2, and BAPTA-AM on Cd2+-induced cytotoxicity might result from directly scavenging ROS and inhibiting oxidative stress-mediated signal transduction, enhancing antioxidant activities and maintaining cell membrane stabilities, and chelating excess calcium(2+) (Ca2+) to hinder its subsequent signal transduction, respectively. Scavenging excessive ROS and inhibiting cellular oxidative stress-mediated signal transduction might be the most effective way to alleviate Cd2+-induced cytotoxicity. Our study provides empirical evidence on the inhibitory effects of AsA, ZnCl2, and BAPTA-AM as specialized inhibitors against Cd2+-induced cellular oxidative stress and cytotoxicity, providing precious ideas for detoxifying toxic environmental metal pollutants.
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Gao, Ke , Du, Yuying , Pan, Na et al. Study on inhibitory effects of AsA, ZnCl2, and BAPTA-AM on Cd2+-induced cell oxidative stress and cytotoxicity by scanning electrochemical microscopy (SECM) technology [J]. | SENSORS & DIAGNOSTICS , 2023 , 3 (1) : 135-146 . |
| MLA | Gao, Ke et al. "Study on inhibitory effects of AsA, ZnCl2, and BAPTA-AM on Cd2+-induced cell oxidative stress and cytotoxicity by scanning electrochemical microscopy (SECM) technology" . | SENSORS & DIAGNOSTICS 3 . 1 (2023) : 135-146 . |
| APA | Gao, Ke , Du, Yuying , Pan, Na , Zhou, Xuewei , Lu, Liping , Wang, Xiayan . Study on inhibitory effects of AsA, ZnCl2, and BAPTA-AM on Cd2+-induced cell oxidative stress and cytotoxicity by scanning electrochemical microscopy (SECM) technology . | SENSORS & DIAGNOSTICS , 2023 , 3 (1) , 135-146 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
A fast scan cyclic voltammetry (FSCV) electrochemical sensor based on multifunctional nanocomposite material Ti3C2/CuS for detection of trace mercury ions (Hg2+) was constructed in this work. Firstly, the high conductivity of Ti3C2 MXene was utilized to improve the charge transfer ability of the sensing interface. Secondly, the determination of Hg2+ with high selectivity was achieved by utilizing the characteristic of CuS solubility product constant being less than HgS. And by comparing the cyclic voltammetry phenomena under conventional scanning speed (0.1 V/s) and ultrafast scanning speed (350 V/s), it was found that on the basis of high-performance interface modification, ultrafast scanning speed could further enhance the current signal significantly. Under the optimal testing conditions, including buffer solution at pH=6, 5 mu L of composite material drop coating volume, and at an adsorption time of 15 min and a scanning rate of 350 V/s, the linear range for detecting Hg2+ was 0.5-50 pmol/L, and the detection limit was 0.5 pmol/L (S/N=3). This sensor had good selectivity, stability and reproducibility, and could be used for determination of trace mercury in actual lake water samples, with recoveries of 97.4%-102.3% and relative standard deviations <3.6%. The sensor was expected to have broad application prospects in emergency and on-site detection.
Keyword ：
Trace mercury ions Trace mercury ions Fast scan cyclic voltammetry Fast scan cyclic voltammetry Electrochemical sensor Electrochemical sensor Chemical modified electrodes Chemical modified electrodes
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Ji, Quan , Lu, Li-Ping . Determination of Trace Mercury Ions by Ti3C2/CuS Composite Modified Glassy Carbon Electrode Combined with Fast Scan Cyclic Voltammetry [J]. | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY , 2023 , 51 (12) : 1915-1923 . |
| MLA | Ji, Quan et al. "Determination of Trace Mercury Ions by Ti3C2/CuS Composite Modified Glassy Carbon Electrode Combined with Fast Scan Cyclic Voltammetry" . | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 51 . 12 (2023) : 1915-1923 . |
| APA | Ji, Quan , Lu, Li-Ping . Determination of Trace Mercury Ions by Ti3C2/CuS Composite Modified Glassy Carbon Electrode Combined with Fast Scan Cyclic Voltammetry . | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY , 2023 , 51 (12) , 1915-1923 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
制备了硫化镉量子点-壳聚糖(CdS-CS)复合物修饰的玻碳电极(GCE),记作CdS-CS/GCE.以卡那霉素为模板分子,3-氨基苯硼酸(APBA)为功能单体,采用循环伏安法在CdS-CS/GCE表面电聚合得到了分子印迹聚合物(MIP)膜,所制备的传感器记作MIP/CdS-CS/GCE.卡那霉素可与传感器表面的MIP特异性结合,占据印迹孔穴,阻断共反应剂K2 S2 O8扩散到电极表面的通路,使电化学发光强度减弱.以传感器在空白溶液中的电化学发光强度(I0)与传感器在卡那霉素标准溶液中的电化学发光强度(I)的差值ΔI(ΔI=I0-I)作为响应信号,在优化的试验条件下,响应信号ΔI与卡那霉素浓度的对数值在1.0×10-11～1.0×10-7 mol·L-1内呈线性关系,相关系数为0.9990,检出限(3S/N)为5×10-12 mol·L-1.按标准加入法对实际样品进行回收试验,回收率为99.9％～103％,测定值的相对标准偏差(n=5)为2.5％～4.3％.
Keyword ：
分子印迹聚合物 分子印迹聚合物 传感器 传感器 卡那霉素 卡那霉素 电化学发光法 电化学发光法 CdS-CS复合物 CdS-CS复合物
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | 孙晨阳 , 康天放 , 鲁理平 et al. 分子印迹电化学发光传感器的制备及其对卡那霉素的测定应用 [J]. | 理化检验（化学分册） , 2023 , 59 (3) : 249-256 . |
| MLA | 孙晨阳 et al. "分子印迹电化学发光传感器的制备及其对卡那霉素的测定应用" . | 理化检验（化学分册） 59 . 3 (2023) : 249-256 . |
| APA | 孙晨阳 , 康天放 , 鲁理平 , 程水源 . 分子印迹电化学发光传感器的制备及其对卡那霉素的测定应用 . | 理化检验（化学分册） , 2023 , 59 (3) , 249-256 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
本文将多壁碳纳米管(MWCNT)修饰到玻碳电极(GCE)界面,并基于臭氧(O3)与靛蓝三磺酸钾(ITS)的灵敏反应,间接实现了水中O3的定量测定.利用扫描电镜和循环伏安法对该修饰电极进行了形貌和电化学性质表征.在最优实验条件下,溶液中ITS的方波伏安(SWV)峰电流在2.0× 10-7～6.4×10-5 mol·L-1浓度范围内随ITS的浓度增大而呈线性增强,检测限为5×10-8mol·L-1.当体系中存在O3时,ITS的SWV峰电流随臭氧浓度的增加而减小,往ITS溶液中加入臭氧溶液前后峰电流减小的差值与O3浓度的对数值在5.0×10-9～1.0×10 5 mol·L-1范围内呈线性关系,检测限为1×10-9 mol·L-1,本方法具有灵敏度高,操作简便,重现性好的优点.
Keyword ：
靛蓝三磺酸钾 靛蓝三磺酸钾 传感器 传感器 方波伏安法 方波伏安法 臭氧 臭氧 多壁碳纳米管 多壁碳纳米管
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | 晚豪 , 康天放 , 鲁理平 . 基于多壁碳纳米管修饰电极的臭氧传感器研究 [J]. | 化学研究与应用 , 2023 , 35 (11) : 2635-2642 . |
| MLA | 晚豪 et al. "基于多壁碳纳米管修饰电极的臭氧传感器研究" . | 化学研究与应用 35 . 11 (2023) : 2635-2642 . |
| APA | 晚豪 , 康天放 , 鲁理平 . 基于多壁碳纳米管修饰电极的臭氧传感器研究 . | 化学研究与应用 , 2023 , 35 (11) , 2635-2642 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
构建了一种基于多功能纳米复合材料Ti3C2/CuS修饰玻碳电极(Ti3C2/CuS/GCE)的电化学传感平台,并采用快速扫描循环伏安法(FSCV)检测痕量汞离子(Hg2+).利用Ti3C2 MXene的高导电性提高传感界面的电荷传递能力,并利用CuS溶度积常数小于HgS的特点实现高选择性测定Hg2+.在Ti3C2/CuS/GCE上,考察了不同扫描速率(0.1和350 V/s)下常规CV和FSCV对Hg2+的分析性能,结果表明,超快扫速可显著增强电流信号.在最佳实验条件下(缓冲溶液pH=6、复合材料滴涂体积为5μL、吸附时间为15 min以及扫描速率为350 V/s),本方法测定Hg2+的线性范围为0.5～50 pmol/L,检出限为0.5 pmol/L(S/N=3),并具有良好的选择性、稳定性和重现性.将本方法用于实际湖水样品中痕量Hg2+的测定,回收率为97.4％～102.3％,相对标准偏差<3.6％,表明本方法在Hg2+的应急检测和现场检测领域具有良好的应用前景.
Keyword ：
快速扫描循环伏安法 快速扫描循环伏安法 痕量汞离子 痕量汞离子 电化学传感器 电化学传感器 化学修饰电极 化学修饰电极
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | 纪权 , 鲁理平 . 基于Ti3C2/CuS纳米复合材料修饰电极快速扫描循环伏安法检测痕量汞离子 [J]. | 分析化学 , 2023 , 51 (12) : 1915-1923 . |
| MLA | 纪权 et al. "基于Ti3C2/CuS纳米复合材料修饰电极快速扫描循环伏安法检测痕量汞离子" . | 分析化学 51 . 12 (2023) : 1915-1923 . |
| APA | 纪权 , 鲁理平 . 基于Ti3C2/CuS纳米复合材料修饰电极快速扫描循环伏安法检测痕量汞离子 . | 分析化学 , 2023 , 51 (12) , 1915-1923 . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
In this study, a new strategy for NO detection based on the aggregation-induced electrochemical luminescence (AIECL) of a ruthenium-based complex and the halogen bonding effect was developed. First, [Ru(phen)(2)(phen-Br-2)](2+) (phen : 1,10-phenanthroline, phen-Br-2 : 3,8-dibromo-1,10-phenanthroline) was synthesized and exhibited aggregation-induced emission (AIE) and AIECL properties in a poor solvent (H2O). [Ru(phen)(2)(phen-Br-2)](2+) exhibited greatly enhanced AIECL properties compared to its AIE intensity. When the volume fraction of water (f(w), v %) in the H2O-acetonitrile (MeCN) system was increased from 30 to 90 %, the photoluminescence and electrochemiluminescence (ECL) intensities were three- and 800-fold that of the pure MeCN system, respectively. Dynamic light scattering and scanning electron microscopy results indicated that [Ru(phen)(2)(phen-Br-2)](2+) aggregated into nanoparticles. AIECL is sensitive to NO because of its halogen bonding effect. The C-Br center dot center dot center dot N bond between [Ru(phen)(2)(phen-Br-2)](2+) and NO increased the distance of complex molecules, resulting in ECL quenching. A detection limit of 2 nM was obtained with 5 orders of magnitude linear range. The combination of the AIECL system and the halogen bond effect expands the theoretical research and applications in biomolecular detection, molecular sensors, and stages of medical diagnosis.
Keyword ：
halogen bonding halogen bonding nitric oxide nitric oxide molecular recognition molecular recognition ruthenium ruthenium aggregation-induced electrochemiluminescence aggregation-induced electrochemiluminescence
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Gao, Yafang , Zhang, Linlin , Wang, Ziqi et al. Aggregation-Induced Electrochemiluminescence and Nitric Oxide Recognition by Halogen Bonding with a Ruthenium(II) Complex [J]. | CHEMPLUSCHEM , 2023 , 88 (3) . |
| MLA | Gao, Yafang et al. "Aggregation-Induced Electrochemiluminescence and Nitric Oxide Recognition by Halogen Bonding with a Ruthenium(II) Complex" . | CHEMPLUSCHEM 88 . 3 (2023) . |
| APA | Gao, Yafang , Zhang, Linlin , Wang, Ziqi , Lu, Liping . Aggregation-Induced Electrochemiluminescence and Nitric Oxide Recognition by Halogen Bonding with a Ruthenium(II) Complex . | CHEMPLUSCHEM , 2023 , 88 (3) . |
| Export to | NoteExpress RIS BibTex |
Abstract ：
Cadmium (Cd) is one of the most prevalent toxic metal pollutants, which is widely distributed in various environmental media and organisms. Literature studies have documented that Cd could stimulate cellular oxidative stress, and the increased intracellular reactive oxygen species (ROS) might destroy certain proteins and DNA and subsequently lead to cell apoptosis. Although several studies have studied the co-exposure between cadmium and other metals, information on the potential effects of Cd and its counterions is still lacking. In the present study, we explored the effects of nitrate and chloride on oxidative stress induced by Cd(ii) at environmental exposure levels in human breast cancer cells (MCF-7) using scanning electrochemical microscopy (SECM). After incubation in CdCl2 or Cd(NO3)(2), ROS production is concentration-dependent and time-dependent, and the variation trend is consistent. When MCF-7 cells were incubated at a constant Cd2+ concentration, it was found that the higher the concentration ratio of Cd(NO3)(2)/CdCl2, the less ROS was generated. Combined with cell-viability, intracellular acidification as well as antioxidants system tests, we observed that nitrate could be reduced to nitrite and then inhibit Cd-induced oxidative stress. Benefitting from real-time in situ imaging of cells by SECM, H2O2 was detected and quantified in a noninvasive way, and the effect of Cd at environmental exposure levels on cellular oxidative stress was explored deeper and more comprehensively. Prospectively, cytotoxicological methods based on the SECM technique would be established to explore toxic pollutant co-exposure issues at environmental exposure levels.
Cite：
Copy from the list or Export to your reference management。
| GB/T 7714 | Pan, Na , Lu, Liping , Zhang, Dongtang et al. Evaluation of the effect of nitrate and chloride on Cd(ii)-induced cell oxidative stress by scanning electrochemical microscopy [J]. | ANALYTICAL METHODS , 2022 , 14 (27) : 2673-2681 . |
| MLA | Pan, Na et al. "Evaluation of the effect of nitrate and chloride on Cd(ii)-induced cell oxidative stress by scanning electrochemical microscopy" . | ANALYTICAL METHODS 14 . 27 (2022) : 2673-2681 . |
| APA | Pan, Na , Lu, Liping , Zhang, Dongtang , Wang, Xiayan . Evaluation of the effect of nitrate and chloride on Cd(ii)-induced cell oxidative stress by scanning electrochemical microscopy . | ANALYTICAL METHODS , 2022 , 14 (27) , 2673-2681 . |
| Export to | NoteExpress RIS BibTex |
Export
| Results： |
Selected to |
| Format： |
