Breast　cancer　has　become　the　first　rank　cancer　in　the　world,and　the　exploration　of　the　pathogenesisand　treatment　of　breast　cancer　deserves　more　and　more　attention.Lipid　metabolism　dysfunction　is　one　of　the　mostprominent　metabolic　changes　in　cancer　cells.It　is　very　important　to　explore　the　changes　of　lipid　metabolism　inbreast　cancer　cells　in　order　to　find　new　diagnostic　indicators　and　therapeutic　targets.This　paper　introduces　theresearch　progress　of　lipid　metabolism　dysfunction　in　breast　cancer　from4aspects:(1)the　expression　of　abnormalfatty　acid　metabolism　in　breast　cancer　from　three　aspects　of　fatty　acid　synthesis,oxidation　and　uptake　and　therelated　research　progress;(2)introduction　to　the　abnormal　expression　of　triglyceride　metabolism　in　breast　cancerfrom　the　aspects　of　triglyceride　synthesis　and　degradation　and　the　related　research　progress;(3)to　introduce　theabnormal　expression　of　cholesterol　synthase　in　breast　cancer　and　the　related　research　progress;(4)to　introducethe　abnormal　expression　of　lipid　metabolism　signaling　pathways　in　breast　cancer　from　five　signaling　pathways,namely　Notch,Hippo,Hedgehog,Wnt　and　mTOR,and　the　related　research　progress.The　aim　is　to　provide　newideas　and　methods　for　targeting　lipid　metabolism　in　the　treatment　of　breast　cancer