An　iron-copper　graphite　felt　(Fe-Cu/HGF)　electrode　was　successfully　prepared　by　heat　treatment　and　impregnation　of　graphite　felt　as　the　support　followed　by　calcination,　and　an　electro-activated　peroxydisulfate　(E-PDS)　system　with　Fe-Cu/HGF　as　the　cathode　was　constructed　to　degrade　Diuron.　This　system　synergistically　activated　PDS　through　electrochemical　processes　and　transition　metal　catalysis.　High-valence　metal　ions　could　be　converted　into　low-valence　metal　ions　by　reduction　at　the　cathode,　and　low-valence　metal　ions　continuously　activated　PDS　to　generate　more　sulfate　radicals　(SO4　&　BULL;-)　and　hydroxyl　radicals　(&　BULL;OH)　to　accelerate　Diuron　degradation.　The　Fe-Cu/HGF　composite　cathode　exhibited　a　performance　superior　to　graphite　felt　(RGF)　obtained　using　pretreatment　only,　including　increased　hydrophilicity,　significantly　increased　number　of　defect　sites　and　larger　electroactive　surface　area.　Under　optimized　experimental　degradation　conditions,　Diuron　could　be　completely　removed　in　35　min,　at　which　time　copper　ion　leaching　was　not　detected　in　the　solution,　while　the　total　iron　ion　concentration　was　0.27　mg　L-1.　Extending　the　reaction　time　to　6　h,　the　amount　of　total　organic　carbon　was　reduced　to　32.2%.　In　addition,　the　free　radicals　that　degraded　Diuron　were　identified　as　mainly　SO4　&　BULL;-　and　&　BULL;OH　with　a　slightly　higher　contribution　of　SO4　&　BULL;-.　The　mechanism　and　pathways　of　Diuron　degradation　in　the　E-PDS　system　were　determined.　The　E-PDS　system　was　successfully　applied　to　the　degradation　of　other　pollutants　and　the　degradation　of　Diuron　in　different　simulated　water　environments.　In　summary,　the　E-PDS　system　using　Fe-Cu/HGF　as　the　cathode　is　a　promising　treatment　method　for　Diuron-containing　wastewater.