Traditional　mechanical　bone　drilling　is　prone　to　heat　generation　and　debris　accumulation　which　will　cause　tissue　damage　in　orthopedic　surgeries.　Therefore,　research　on　contactless　laser　bone　drilling　has　become　a　mainstream　trend　in　the　development　of　bone　surgery.　This　study　presents　a　laser　rapid　drilling　strategy　for　bone　surgery　with　minimizing　thermal　osteonecrosis　and　debris　based　on　the　design　of　dynamic　focusing　and　spreading　droplet　cooling.　The　laser　drilled　hole　suffered　from　low　temperature　(T-max　=　46.2　?)　under　clinically　accepted　threshold　of　47　?,　presenting　osteocyte-filled　lacunas,　visible　Haversian　canals　and　increased　pullout　strength　when　compared　with　that　following　mechanically　drilling.　An　intact　bone　column　without　debris　was　extracted　from　a　4-mm-deep　hole　in　vitro　on　a　sheep　tibia　which　provides　a　clean　surgical　method　with　increased　drilling　rate　of　0.94　mm(3)/s.　The　criteria　dimensionless　We　constant　related　to　spreading　droplets　leading　to　effective　heat　transfer　is　determined　as2.8　x　10(3)　x　Re-1/2　＜=　We　＜=　1.9　x　10(-2)　x　Re-7,　yielding　a　high　convective　coefficient　of　0.11　W/mm(2).K　for　cooling.　The　comprehensive　results　of　laser　bone　drilling　proved　the　effectiveness　of　the　presented　technology　and　setup,　which　is　significant　in　realizing　rapid,　debris-free　orthopedic　surgery.　(C)　2022　The　Author(s).　Published　by　Elsevier　Ltd.