Patients　who　has　been　implanted　with　hip　implant　usually　undergo　revision　surgery.　The　reason　is　that　high　stiff　implants　would　cause　non-physiological　distribution　loadings,　which　is　also　known　as　stress　shielding,　and　finally　lead　to　bone　loss　and　aseptic　loosening.　Titanium　implants　are　widely　used　in　human　bone　tissues;　however,　the　subsequent　elastic　modulus　mismatch　problem　has　become　increasingly　serious,　and　can　lead　to　stress-shielding　effects.　This　study　aimed　to　develop　a　parametric　design　methodology　of　porous　titanium　alloy　hip　implant　with　gradient　elastic　modulus,　and　mitigate　the　stress-shielding　effect.　Four　independent　adjustable　dimensions　of　the　porous　structure　were　parametrically　designed,　and　the　Kriging　algorithm　was　used　to　establish　the　mapping　relationship　between　the　four　adjustable　dimensions　and　the　porosity,　surface-to-volume　ratio,　and　elastic　modulus.　Moreover,　the　equivalent　stress　on　the　surface　of　the　femur　was　optimized　by　response　surface　methodology,　and　the　optimal　gradient　elastic　modulus　of　the　implant　was　obtained.　Finally,　through　the　Kriging　approximation　model　and　optimization　results　of　the　finite　element　method,　the　dimensions　of　each　segment　of　the　porous　structure　that　could　effectively　mitigate　the　stress-shielding　effect　were　determined.　Experimental　results　demonstrated　that　the　parameterized　design　method　of　the　porous　implant　with　gradient　elastic　modulus　proposed　in　this　study　increased　the　strain　value　on　the　femoral　surface　by　17.1%　on　average.　Consequently,　the　stress-shielding　effect　of　the　femoral　tissue　induced　by　the　titanium　alloy　implant　was　effectively　mitigated.　(Figure　presented.).　Copyright　©　2022　Gao,　Zhao,　Wang,　Liu　and　Liu.