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Author:

Li, Ziwei (Li, Ziwei.) | Xu, Qi (Xu, Qi.) | Sun, Ge (Sun, Ge.) | Jia, Runqing (Jia, Runqing.) | Yang, Lin (Yang, Lin.) | Liu, Guoli (Liu, Guoli.) | Hao, Dongmei (Hao, Dongmei.) | Zhang, Song (Zhang, Song.) | Yang, Yimin (Yang, Yimin.) | Li, Xuwen (Li, Xuwen.) | Zhang, Xinyu (Zhang, Xinyu.) | Lian, Cuiting (Lian, Cuiting.)

Indexed by:

Scopus SCIE

Abstract:

Pre-eclampsia (PE) is a type of hypertensive disorder during pregnancy, which is a serious threat to the life of mother and fetus. It is a placenta-derived disease that results in placental damage and necrosis due to systemic small vessel spasms that cause pathological changes such as ischemia and hypoxia and oxidative stress, which leads to fetal and maternal damage. In this study, four types of risk factors, namely, clinical epidemiology, hemodynamics, basic biochemistry, and biomarkers, were used for the initial selection of model parameters related to PE, and factors that were easily available and clinically recognized as being associated with a higher risk of PE were selected based on hospital medical record data. The model parameters were then further analyzed and screened in two subgroups: early-onset pre-eclampsia (EOPE) and late-onset pre-eclampsia (LOPE). Dynamic gestational week prediction model for PE using decision tree ID3 algorithm in machine learning. Performance of the model was: macro average (precision = 76%, recall = 73%, F1-score = 75%), weighted average (precision = 88%, recall = 89%, F1-score = 89%) and overall accuracy is 86%. In this study, the addition of the dynamic timeline parameter "gestational week " made the model more convenient for clinical application and achieved effective PE subgroup prediction.

Keyword:

hypertensive disorders of pregnancy decision tree pre-eclampsia dynamic prediction model

Author Community:

  • [ 1 ] [Li, Ziwei]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 2 ] [Sun, Ge]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 3 ] [Jia, Runqing]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 4 ] [Yang, Lin]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 5 ] [Hao, Dongmei]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 6 ] [Zhang, Song]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 7 ] [Yang, Yimin]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 8 ] [Li, Xuwen]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 9 ] [Zhang, Xinyu]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 10 ] [Lian, Cuiting]Beijing Univ Technol, Fac Environm & Life Sci, Beijing, Peoples R China
  • [ 11 ] [Xu, Qi]Beijing Int Base Sci & Technol Cooperat, Intelligent Physiol Measurement & Clin Translat, Beijing, Peoples R China
  • [ 12 ] [Sun, Ge]Beijing Int Base Sci & Technol Cooperat, Intelligent Physiol Measurement & Clin Translat, Beijing, Peoples R China
  • [ 13 ] [Yang, Lin]Beijing Int Base Sci & Technol Cooperat, Intelligent Physiol Measurement & Clin Translat, Beijing, Peoples R China
  • [ 14 ] [Hao, Dongmei]Beijing Int Base Sci & Technol Cooperat, Intelligent Physiol Measurement & Clin Translat, Beijing, Peoples R China
  • [ 15 ] [Zhang, Song]Beijing Int Base Sci & Technol Cooperat, Intelligent Physiol Measurement & Clin Translat, Beijing, Peoples R China
  • [ 16 ] [Yang, Yimin]Beijing Int Base Sci & Technol Cooperat, Intelligent Physiol Measurement & Clin Translat, Beijing, Peoples R China
  • [ 17 ] [Li, Xuwen]Beijing Int Base Sci & Technol Cooperat, Intelligent Physiol Measurement & Clin Translat, Beijing, Peoples R China
  • [ 18 ] [Zhang, Xinyu]Beijing Int Base Sci & Technol Cooperat, Intelligent Physiol Measurement & Clin Translat, Beijing, Peoples R China
  • [ 19 ] [Lian, Cuiting]Beijing Int Base Sci & Technol Cooperat, Intelligent Physiol Measurement & Clin Translat, Beijing, Peoples R China
  • [ 20 ] [Liu, Guoli]Peking Univ, Peoples Hosp, Dept Obstet, Beijing, Peoples R China

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Source :

FRONTIERS IN PHYSIOLOGY

Year: 2022

Volume: 13

4 . 0

JCR@2022

4 . 0 0 0

JCR@2022

ESI Discipline: BIOLOGY & BIOCHEMISTRY;

ESI HC Threshold:43

JCR Journal Grade:2

CAS Journal Grade:2

Cited Count:

WoS CC Cited Count: 3

SCOPUS Cited Count: 4

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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