Aim:　To　evaluate　whether　there　is　a　significant　relationship　between　hemodynamic　models　and　pre-eclampsia　outcomes.　Method:　A　controlled　experimental　study　was　performed.　We　analyzed　2910　hemodynamic　series　systematically　sampled　from　970　pregnant　women　three　times　every　2　weeks　from　the　definite　diagnosis　of　pre-eclampsia　until　delivery.　Women　were　divided　into　three　groups　based　on　total　peripheral　resistance　(TPR):　a　low-TPR　group,　a　normal-TPR　group　and　a　high-TPR　group.　Every　group　was　divided　into　three　subgroups　based　on　cardiac　index　(CI):　a　low-CI　subgroup,　a　normal-CI　group　and　high-CI　group.　Common　lab　tests,　electrocardiographic　examination,　fundus　examination,　cardiac　function,　liver　function　and　kidney　function　were　measured　after　every　hemodynamic　monitoring.　Primary　outcomes　included　various　maternal　and　neonatal　morbidity　and　neonatal　and　infant　mortality.　Results:　In　our　study　we　found　seven　hemodynamic　models　in　pre-eclampsia　during　the　third　trimester　of　pregnancy.　No　significant　differences　in　maternal　age,　weight,　and　height　were　observed　between　the　three　groups.　The　low-TPR　and　normal-TPR　groups　showed　better　disease　results　than　the　high-TPR　group　in　respect　of　HELLP　(P　＜　0.01),　lung　edema　(P　＜　0.01),　acute　renal　failure　(P　＜　0.01),　heart　failure　(P　＜　0.01),　neonatal　intensive　care　unit　admission　(P　＜　0.01),　infant　weight　(P　＜　0.01),　neonatal　mortality　(P　＜　0.01)　and　infant　mortality　(P　＜　0.01).　The　low-TPR　group　had　better　results　than　the　normal-TPR　group　in　respect　of　eclampsia　(P　＜　0.01),　liver　hemorrhage　(P　＜　0.01),　birthweight　(P　＜　0.01)　and　gestational　week　at　birth　(P　＜　0.05).　Conclusion:　Among　all　the　subgroups,　the　highest　maternal　and　neonatal　morbidity　was　in　the　high-TPR-high-CI　subgroup.　There　is　clear　relationship　between　hemodynamic　and　disease　outcomes　during　the　third　trimester.