Semiconductor　nanowires　have　demonstrated　excellent　electronic　and　optoelectronic　properties.　When　integrated　into　photodetectors,　excellent　device　performance　can　be　easily　attained.　Apart　from　the　exceptional　performance,　these　nanowires　can　also　enable　robust　and　mechanically　flexible　photodetectors　for　various　advanced　utilizations　that　the　rigid　counterparts　cannot　perform.　These　unique　applications　include　personal　healthcare,　next-generation　robotics　and　many　others.　In　this　review,　we　would　first　discuss　the　nanowire　fabrication　techniques　as　well　as　the　assembly　methods　of　constructing　large-scale　nanowire　arrays.　Then,　the　recent　development　of　flexible　photodetectors　based　on　these　different　nanowire　material　systems　is　evaluated　in　detail.　At　the　same　time,　we　also　introduce　some　recent　advancement　that　allows　individual　photodetectors　to　integrate　into　a　more　complex　system　for　advanced　deployment.　Finally,　a　short　conclusion　and　outlook　of　challenges　faced　in　the　future　of　the　community　is　presented.