The　frequency　of　earthquake-triggered　landslides　has　increased　in　recent　years,　thus　urgently　necessitating　the　development　of　prevention　and　control　strategies　to　mitigate　such　geological　disasters.　Pile-anchor　structures　can　overcome　the　problems　of　the　excessive　pile　body　bending　moment　and　limited　slope　reinforcement　range　when　the　slope　is　separately　reinforced　by　a　single　pile　and　anchor.　In　this　paper,　a　refined　dynamic　centrifuge　shaking　table　test　was　performed　on　a　rock　slope　reinforced　by　a　pile-anchor　structure　based　on　the　non-linear　charac-teristics　of　the　rock-soil　structure　and　the　mechanical　parameters.　The　elevation　amplification　effect　of　the　peak　ground　acceleration　is　analyzed　from　the　perspective　of　the　time　history　and　frequency　spectrum,　which　fully　reveal　the　synergistic　mechanism　of　the　pile-anchor　reinforcement　system.　The　failure　evolution　process　of　an-chor　tensile　failure　and　trailing　edge　cracking　occur　alongside　overall　sliding　is　revealed　by　assessing　the　seismic　response　of　the　acceleration,　displacement,　anchor　tension,　pile　bending　moment　and　soil　pressure　under　multi-level　seismic　loading　conditions.　The　results　prove　that　pile-anchor　structures　significantly　reduce　permanent　displacement　and　enhance　the　stability　of　slope,　and　further　provide　data　and　theoretical　support　for　slope　seismic　design　using　pile-anchor　reinforcement,　which　can　effectively　protect　human　safety　and　property　in　earthquake-prone　areas.