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Author:

Zeng, Yan (Zeng, Yan.) | Tsui, Po-Hsiang (Tsui, Po-Hsiang.) | Pang, Kunjing (Pang, Kunjing.) | Bin, Guangyu (Bin, Guangyu.) | Li, Jiehui (Li, Jiehui.) | Lv, Ke (Lv, Ke.) | Wu, Xining (Wu, Xining.) | Wu, Shuicai (Wu, Shuicai.) (Scholars:吴水才) | Zhou, Zhuhuang (Zhou, Zhuhuang.)

Indexed by:

EI Scopus SCIE

Abstract:

The segmentation of cardiac chambers and the quantification of clinical functional metrics in dynamic echo-cardiography are the keys to the clinical diagnosis of heart disease. Identifying the end-diastolic frames (EDFs) and end-systolic frames (ESFs) and manually segmenting the left ventricle in the echocardiographic cardiac cycle before obtaining the left ventricular ejection fraction (LVEF) is a time-consuming and tedious task for clinicians. In this work, we proposed a deep learning-based fully automated echocardiographic analysis method. We pro-posed a multi-attention efficient feature fusion network (MAEF-Net) to automatically segment the left ventricle. Then, EDFs and ESFs in all cardiac cycles were automatically detected to compute LVEF. The MAEF-Net method used a multi-attention mechanism to guide the network to capture heartbeat features effectively, while sup-pressing noise, and incorporated deep supervision mechanism and spatial pyramid feature fusion to enhance feature extraction capabilities. The proposed method was validated on the public EchoNet-Dynamic dataset (n = 1226). The Dice similarity coefficient (DSC) of the left ventricular segmentation reached (93.10 +/- 2.22)%, and the mean absolute error (MAE) of cardiac phase detection was (2.36 +/- 2.23) frames. The MAE for predicting LVEF was 6.29 %. The proposed method was also validated on a private clinical dataset (n = 22). The DSC of the left ventricular segmentation reached (92.81 +/- 2.85)%, and the MAE of cardiac phase detection was (2.25 +/- 2.27) frames. The MAE for predicting LVEF was 5.91 %, and the Pearson correlation coefficient r reached 0.96. The proposed method may be used as a new method for automatic left ventricular segmentation and quantitative analysis in two-dimensional echocardiography. Our code and trained models will be made available publicly at https://github.com/xiaojinmao-code/MAEF-Net.

Keyword:

Ejection fraction Left ventricular segmentation Cardiac phase detection Deep learning Echocardiography

Author Community:

  • [ 1 ] [Zeng, Yan]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing 100124, Peoples R China
  • [ 2 ] [Bin, Guangyu]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing 100124, Peoples R China
  • [ 3 ] [Li, Jiehui]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing 100124, Peoples R China
  • [ 4 ] [Wu, Shuicai]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing 100124, Peoples R China
  • [ 5 ] [Zhou, Zhuhuang]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing 100124, Peoples R China
  • [ 6 ] [Tsui, Po-Hsiang]Chang Gung Univ, Coll Med, Dept Med Imaging & Radiol Sci, Taoyuan, Taiwan
  • [ 7 ] [Tsui, Po-Hsiang]Chang Gung Univ, Inst Radiol Res, Taoyuan, Taiwan
  • [ 8 ] [Tsui, Po-Hsiang]Chang Gung Mem Hosp Linkou, Dept Pediat, Div Pediat Gastroenterol, Taoyuan, Taiwan
  • [ 9 ] [Pang, Kunjing]Chinese Acad Med Sci & Peking Union Med Coll, Fuwai Hosp, Natl Ctr Cardiovasc Dis, State Key Lab Cardiovasc Dis,Dept Echocardiog, Beijing 100037, Peoples R China
  • [ 10 ] [Li, Jiehui]Chinese Acad Med Sci & Peking Union Med Coll, Natl Ctr Cardiovasc Dis, Beijing 100037, Peoples R China
  • [ 11 ] [Li, Jiehui]Chinese Acad Med Sci & Peking Union Med Coll, Fuwai Hosp, State Key Lab Cardiovasc Dis, Dept Cardiac Surg, Beijing 100037, Peoples R China
  • [ 12 ] [Lv, Ke]Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Ultrasound, Beijing 100730, Peoples R China
  • [ 13 ] [Wu, Xining]Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Ultrasound, Beijing 100730, Peoples R China

Reprint Author's Address:

  • [Wu, Shuicai]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing 100124, Peoples R China;;[Zhou, Zhuhuang]Beijing Univ Technol, Fac Environm & Life, Dept Biomed Engn, Beijing 100124, Peoples R China;;

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Source :

ULTRASONICS

ISSN: 0041-624X

Year: 2023

Volume: 127

4 . 2 0 0

JCR@2022

ESI Discipline: CLINICAL MEDICINE;

ESI HC Threshold:14

Cited Count:

WoS CC Cited Count: 20

SCOPUS Cited Count: 30

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 6

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