Signal　sampling　issue　has　been　extensively　studied　based　on　a　single　sampling　functional　over　classical　Lebesgue　spaces.　This　paper　focuses　on　discussing　the　signal　reconstruction　and　error　analysis　based　on　multiple　sampling　functionals　over　mixed　Lebesgue　spaces.　We　firstly　explore　the　stabilities　for　two　kinds　of　sampling　functionals,　respectively.　Then　the　corresponding　iterative　reconstruction　algorithms　are　established.　Finally,　the　error　between　the　reconstruction　signal　in　the　presence　of　noisy　and　the　original　signal　f　is　analyzed.