The　eastern　China　presented　the　most　serious　O3　pollution　and　increasingly　prominent　regional　characteristics.　To　understand　the　transport　characteristics　of　O3　and　its　precursors　and　identify　their　potential　relationships　are　of　great　guiding　significance　for　interregional　joint　prevention　and　control.　In　this　study,　the　annual　and　seasonal　transport　networks　of　O3　and　its　precursors　(NO2　and　CO)　during　2017–2021　were　constructed　by　applying　the　complex　network　method　to　air　quality　observations.　And　the　key　spatial　clusters,　the　spillover　paths　and　the　potential　links　among　pollutants　were　comprehensively　analyzed　based　on　the　topological　characteristic　analysis　of　the　established　air　pollutant　transport　networks.　As　the　results　showed,　O3　pollution　in　the　eastern　China　was　affected　by　active　regional　transports　of　O3　and　its　precursors.　Regional　transports　of　O3,　NO2,　and　CO　were　more　prominent　in　autumn　and　showed　high　synchronization.　The　regional　transport　of　precursors,　especially　NOx,　was　an　important　cause　of　regional　O3　pollution.　Air　pollutant　transport　characteristics　varied　with　seasons　and　regions,　which　demonstrating　the　importance　of　regulating　seasonal　and　regional　differentiated　joint　prevention　and　control　strategies,　especially　for　NOx.　The　results　of　this　study　can　provide　science-based　guidance　for　the　regional　cooperative　control　of　O3　pollution　in　the　eastern　China,　and　the　application　of　complex　networks　can　also　provide　a　new　methodological　perspective　for　the　study　of　air　pollution　transmission.　©　2023　Elsevier　B.V.