Considering　that　the　influent　of　Anammox　process　must　contain　two　substrates,　NO2--N　and　NH4+-N,　and　it　could　only　be　denitrified.　In　order　to　further　realize　phosphorus　removal　on　this　basis,　this　study　proposed　to　combine　phosphorus　removal　and　nitrogen　removal　with　partial　nitrification　technology,　namely　partial　nitrification　and　denitrifying　phosphorus　removal　tandem　Anammox　process:　the　partial　nitrification　and　denitrification　phosphorus　removal　unit　was　the　first　to　pass　into　domestic　sewage　to　convert　NH4+-N　to　NO2--N　and　remove　part　of　COD.　Part　of　the　effluent　was　mixed　with　domestic　sewage　and　enters　the　anaerobic　ammonium　oxidation　unit.　At　the　same　time,　the　partial　nitrification　and　denitrification　phosphorus　removal　unit　was　denitrified　and　absorbed　phosphorus　under　the　hypoxia　state,　and　the　effluent　of　the　two　treatment　units　was　mixed　and　discharged　after　the　end　of　the　reaction.　The　experimental　results　showed　that　controlling　the　influent　mixing　ratio　to　be　4.2　could　ensure　that　the　values　of　C/N　and　NO2-N/NH4+-N　in　the　Anammox　unit　were　2　and　1.5,　respectively,　the　average　NO2--N/NH4+-N=1.41,　NO3--N/NH4+-N=0.12,　Anammox　nitrogen　85.2%　on　average,　denitrification　and　Anammox　coupling　reaction　was　good.　After　stable　operation　of　the　whole　system,　the　effluent　COD,　P,　NH4+-N,　NO2--N　and　NO3--N　concentrations　were　15.2,　0.85,　0.59,　5.56　and　3.33mg/L,　respectively,　and　the　TN　removal　rate　was　89.4%.　The　PNDPR-Anammox　coupling　new　process　successfully　realized　the　efficient　treatment　of　simulated　domestic　sewage.　©　2021,　Editorial　Board　of　China　Environmental　Science.　All　right　reserved.