With　the　development　of　medical　technology　and　materials　science,　the　structure　optimization　method　of　bioabsorbable　materials　for　implantable　medical　devices　becomes　more　and　more　important,　and　the　absorbable　interface　screw　is　the　most　representative　device　in　implantable　medical　devices.　Based　on　the　previous　parametric　design　method　for　the　loading　and　structural　characteristics　of　the　interface　screw,　this　paper　assembled　the　interface　screw　and　cancellous　bone　with　the　tunnel　hole　and　simulated　the　graft　fixation　after　cruciate　ligaments　surgery.　In　this　study,　through　the　finite　element　method,　the　mechanical　properties　of　interface　screws　with　different　structural　parameters　obtained　by　parametric　design　were　comprehensively　evaluated　from　the　aspects　of　stress　and　strain　energy　density.　©　Published　under　licence　by　IOP　Publishing　Ltd.