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Biological experiments are an important means of studying calcium transients in myocardial cells, but it is difficult to conduct simultaneous interactions between various components within the cell. This article constructs a geometric model of the occurrence space of atrial sarcoplasmic reticulum calcium transient, and constructs a dynamic model based on the physiological mechanism of sarcoplasmic reticulum calcium transient. By using the constructed dynamic model for the numerical calculation of sarcoplasmic reticulum calcium transient in atrial muscle, most of the results are in line with biological experimental results. In addition, this numerical model can also simulate the morphology of various sarcoplasmic reticulum calcium transients in myocardial cells by optimizing the dynamic model of sarcoplasmic reticulum calcium transients and adjusting parameters. © 2024 SPIE.
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ISSN: 0277-786X
Year: 2024
Volume: 13219
Language: English
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ESI Highly Cited Papers on the List: 0 Unfold All
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30 Days PV: 3
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