Pile　and　anchor　structures　are　extensively　employed　for　slope　stabilization.　However,　their　dynamic　response　under　seismic　loading　remains　unclear　and　current　seismic　designs　primarily　use　the　pseudo-static　method.　Here,　a　three-dimensional　numerical　simulation　of　the　dynamic　behavior　of　a　bedding　rock　slope　supported　by　pile-anchor　systems　under　earthquakes　is　conducted.　The　dynamic　calculation　for　the　slope　subjected　to　seismic　forces　with　varying　excitation　directions　and　acceleration　amplitudes　is　performed.　The　dynamic　behavior　of　both　the　slope　and　the　pile-anchor　system　is　investigated　with　respect　to　the　slope＇s　failure　mode,　the　dynamic　soil　pressure　behind　the　pile,　the　anchor　axial　force,　the　bending　moment,　and　the　lateral　displacement　of　the　pile.　The　results　indicate　that　the　anti-slide　piles　cause　a　reflective　and　superposition　effect　on　seismic　waves　within　weak　rock　layers.　As　the　input　seismic　intensity　increases,　the　axial　force　in　the　anchor　cables　also　increases,　with　the　peak　axial　force　occurring　during　the　main　energy　phase　of　the　seismic　waves.　The　dynamic　soil　pressure　acting　behind　the　piles　varies　with　the　stratification　of　the　slope　rock　layers,　with　lower　peak　dynamic　earth　pressure　observed　in　weak　layers.　The　weak　layers　on　the　slope　surface　experience　through-shear　failure.　Under　strong　seismic　loading,　the　structural　element　state　undergoes　significant　changes.