In　order　to　study　the　hyperelastic　properties　of　the　artery,　this　paper　established　two　kinds　of　isotropic　hyperelastic　models　of　artery.　The　stress-strain　relations　of　the　artery　under　biaxial　loadings　were　simulated　by　using　3D　finite　element　method.　It　is　shown　that　in　certain　range　of　deformation,　the　stress-strain　relations　of　isotropic　artery　can　exactly　be　expressed　by　the　present　two　models.　It　is　also　concluded　that　the　orientations　and　properties　of　blended　fibers　in　the　artery　walls　contribute　to　the　macro-properties　of　the　artery.