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Author:

Gao, Hongjian (Gao, Hongjian.) | Wang, Xiaoru (Wang, Xiaoru.) | Wu, Shuicai (Wu, Shuicai.) (Scholars:吴水才) | Zhou, Zhuhuang (Zhou, Zhuhuang.) | Bai, Yanping (Bai, Yanping.) | Ai, Haiming (Ai, Haiming.)

Indexed by:

EI Scopus SCIE

Abstract:

It is critical for microwave ablation (MWA) treatment planning to evaluate the changes of thermal coagulation zones. In MWA procedures, the shapes and sizes of thermal coagulation zones are gradually evolving over time. To this end, a novel characterization and mapping method of thermal coagulation zones is presented in this article. Firstly, finite element method (FEM) models of temperature distributions for 40, 45, 50, 55, and 60W microwave ablations were built to derive thermal ablation data of ex vivo porcine livers and were compared with experimental results. Secondly, growth models of characteristic lengths were fitted. Finally, characterization functions of thermal coagulation zones were developed using these growth models. In addition, shape variation factors were incorporated to handle the minor shape variations of thermal coagulation zones. Experimental results showed that these characterization functions could accurately represent the changes of thermal coagulation zones. The standard deviations between prediction results and simulated values were less than 1 mm. The comparative results were statistically analyzed by paired t test (P>0.05), indicating no significant differences. The proposed method can simply and effectively predict the changes of MWA coagulation zones with time, thus providing reliable coagulation dimensions for the thermal ablation therapies.

Keyword:

microwave ablation shape variation factor 2-D mapping coagulation zone growth model

Author Community:

  • [ 1 ] [Gao, Hongjian]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 PingLeYuan, Beijing 100124, Peoples R China
  • [ 2 ] [Wang, Xiaoru]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 PingLeYuan, Beijing 100124, Peoples R China
  • [ 3 ] [Wu, Shuicai]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 PingLeYuan, Beijing 100124, Peoples R China
  • [ 4 ] [Zhou, Zhuhuang]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 PingLeYuan, Beijing 100124, Peoples R China
  • [ 5 ] [Bai, Yanping]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 PingLeYuan, Beijing 100124, Peoples R China
  • [ 6 ] [Ai, Haiming]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 PingLeYuan, Beijing 100124, Peoples R China

Reprint Author's Address:

  • 吴水才

    [Wu, Shuicai]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 PingLeYuan, Beijing 100124, Peoples R China

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Source :

INTERNATIONAL JOURNAL OF RF AND MICROWAVE COMPUTER-AIDED ENGINEERING

ISSN: 1096-4290

Year: 2019

Issue: 6

Volume: 29

1 . 7 0 0

JCR@2022

ESI Discipline: ENGINEERING;

ESI HC Threshold:136

JCR Journal Grade:3

Cited Count:

WoS CC Cited Count: 4

SCOPUS Cited Count: 6

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 13

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