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Author:

Gao, Hongjian (Gao, Hongjian.) | Wang, Xiaoru (Wang, Xiaoru.) | Wu, Shuicai (Wu, Shuicai.) (Scholars:吴水才) | Zhou, Zhuhuang (Zhou, Zhuhuang.) | Bai, Yanping (Bai, Yanping.) | Wu, Weiwei (Wu, Weiwei.)

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Scopus SCIE PubMed

Abstract:

Purpose: To optimize treatment schemes using 2450-MHz microwave ablation (MWA), a novel conformal coverage method based on bipolar-angle mapping is proposed that determines whether a liver tumor is completely encompassed by thermal coagulation zones. Materials and methods: Firstly, three-dimensional (3-D) triangular mesh data of liver tumors were reconstructed from clinical computed tomography (CT) slices using the Marching cubes (MC) algorithm. Secondly, characterization models of thermal coagulation zones were established based on finite element simulation results of 40, 45, 50, 55, and 60W ablations. Finally, coagulation zone models and tumor surface data were mapped and fused on a two-dimensional (2-D) plane to achieve conformal coverage of liver tumors by comparing the corresponding polar radii. Results: Optimal parameters for ablation treatment of liver tumors were efficiently obtained with the proposed conformal coverage method. Fifteen liver tumors were obtained with maximal diameters of 12.329-78.612mm (mean +/- standard deviation, 39.094 +/- 19.447mm). The insertion positions and orientations of the MWA antenna were determined based on 3-D reconstruction results of these tumors. The ablation patterns and durations of tumors were planned according to the minimum mean standard deviations between the ablative margin and tumor surface. Conclusion: The proposed method can be applied to computer-assisted MWA treatment planning of liver tumors, and is expected to guide clinical procedures in future.

Keyword:

coagulation zone treatment planning three-dimensional reconstruction liver tumor Conformal coverage microwave ablation

Author Community:

  • [ 1 ] [Gao, Hongjian]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 2 ] [Wang, Xiaoru]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 3 ] [Wu, Shuicai]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 4 ] [Zhou, Zhuhuang]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 5 ] [Bai, Yanping]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 6 ] [Wu, Weiwei]Capital Med Univ, Coll Biomed Engn, Beijing, Peoples R China

Reprint Author's Address:

  • 吴水才

    [Wu, Shuicai]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China

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Source :

INTERNATIONAL JOURNAL OF HYPERTHERMIA

ISSN: 0265-6736

Year: 2019

Issue: 1

Volume: 36

Page: 591-605

3 . 1 0 0

JCR@2022

ESI Discipline: CLINICAL MEDICINE;

ESI HC Threshold:137

JCR Journal Grade:2

Cited Count:

WoS CC Cited Count: 9

SCOPUS Cited Count: 10

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 7

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