Polyvinylidene　fluoride　(PVDF)　microfiltration　(MF)　membranes　with　enhanced　perm-selectivity　and　antifouling　property　were　successfully　prepared　by　incorporating　GO-SiO2　nanoparticles　into　PVDF　matrix.　Under　the　optimal　GO-SiO2/PVP　ratio　of　0.5/1　(wt./wt.)　in　the　casting　solution,　the　prepared　PVDF/GO-SiO2　hybrid　membrane　exhibited　improved　perm-selectivity　with　a　water　flux　of　850　L/(m(2)　h)　and　HA　rejection　of　92%.　Compared　with　the　pristine　PVDF　membrane,　the　optimized　hybrid　membrane　exhibited　89%　higher　water　flux　without　sacrificing　its　rejection,　increased　porosity　and　hydrophilicity.　In　addition,　the　PVDF/GO-SiO2　hybrid　membrane　also　showed　satisfactory　antifouling　performance　(the　lower　irreversible　fouling　ratio　of　37.4%　and　high　recovery　ratio　of　62%)　and　good　stability　in　the　long-term　performance　test.　(C)　2017　Taiwan　Institute　of　Chemical　Engineers.　Published　by　Elsevier　B.V.　All　rights　reserved.