Metal-organic　frameworks　(MOFs)　are　widely　employed　as　functional　materials　in　various　fields,　while　intriguing　properties　for　specific　applications　have　been　pursued　all　along　with　their　development.　Herein,　we　adopt　a　ligand　substitution　strategy　to　functionalize　the　mesoporous　IRMOF-74-IV　for　multivariate　MOF　catalysts.　With　similar　size　and　geometry,　the　porphyrin　ligand　4,4　＇-(porphyrin-5,15-diyl)bis(2-hydroxybenzolate)　(PBHB2-)　was　mixed　with　the　3,3　＇＇＇-dihydroxy-2　＇,2　＇＇,5　＇,5　＇＇-tetramethyl-[1,1　＇:4　＇,1　＇＇:4　＇＇,1　＇＇＇-quaterphenyl]-4,4　＇＇＇-dicarboxylate　(L-IV2-)　ligand　in　synthesis,　giving　porphyrin　functionalized　IRMOF-74-IV　analogs.　Compared　with　IRMOF-74-IV,　the　IRMOF-74-IV-PBHBX-M　series　show　improved　stability　and　performance　in　photocatalytic　CO2　reduction.　After　tuning　the　contents　of　porphyrin　ligand　and　the　species　of　metal　ion,　IRMOF-74-IV-PBHB45%-Cu　demonstrates　to　be　the　best　as　an　efficient　photocatalyst　for　the　CO2-to-CO　conversion.　This　work　has　achieved　to　tailor　extant　MOFs　through　a　mixed-ligand　approach,　which　would　contribute　to　more　multivariate　materials　and　unlock　new　opportunities　for　their　applications.