Metal　organic　frameworks　(MOFs)　have　been　widely　concerned　by　researchers　as　catalytic　materials.　In　this　work,　nitrogen　doped　Fe,　Co　bimetallic　MOF　named　FeCo/N-MOF　was　prepared　by　＂one-pot＂　hydrothermal　method　as　a　catalyst　for　activating　persulfate　to　degrade　tetracycline.　The　hexagonal　spindle　crystals　morphology　and　porous　structure　were　observed　on　the　FeCo/N-MOF.　The　X-ray　photoelectron　spectroscopy　(XPS)　showed　that　Fe(III)　and　Co(II)　were　the　main　active　sites　and　the　presence　of　pyrrole　N　was　positive　to　the　catalysis.　The　different　conditions　of　catalyst　dosage,　pH　and　persulfate　concentration　were　discussed　to　further　understand　the　mechanism　of　FeCo/N-MOF　on　tetracycline　(TC)　degradation.　The　results　revealed　that　about　99%　of　tetracycline　was　degraded　in　150　min　when　FeCo/N-MOF　was　0.4　g/L　and　persulfate　was　5　mmol/L　in　a　wide　range　of　pH　from　3　to　9.　Moreover,　the　reaction　stoichiometric　efficiency　of　persulfate　was　6.13%.　There　were　radicals　and　non-radical　pathways　in　the　process　of　TC　degradation　and　the　superoxide　radical　was　the　main　active　sub-stances.　This　study　suggested　that　FeCo/N-MOF　was　of　great　potential　in　persulfate　activation　for　water　puri-fication,　which　also　provided　a　platform　for　MOF-derived　catalysts　in　the　field　of　advanced　oxidation.