Non-suicidal　self-injury　has　been　increasingly　acknowledged　as　a　health　problem.　However,　the　association　of　cyberbullying　victimization　with　non-suicidal　self-injury　and　the　mechanisms　connecting　this　link　have　not　been　sufficiently　studied.　Therefore,　the　current　study　aimed　to　test　the　link　between　cyberbullying　victimization　and　non-suicidal　self-injury　and　to　explore　the　mediating　roles　of　basic　psychological　needs　satisfaction　and　the　moderating　role　of　self-compassion　in　this　relation.　A　sample　of　1007　senior　high　students　participated　in　the　current　study　and　completed　multiple　questionnaires　on　cyberbullying　victimization,　basic　psychological　needs　satisfaction,　non-suicidal　self-injury,　and　self-compassion.　The　bivariate　correlations　between　variables,　mediation　model,　and　moderated　mediation　model　were　tested　by　correlation　analysis　and　Model　4　and　Model　8　of　the　PROCESS　macro,　respectively.　The　results　indicated　that　cyberbullying　victimization　was　significantly　and　positively　associated　with　non-suicidal　self-injury.　Autonomy　needs　satisfaction　mediated　the　relationship　between　cyberbullying　victimization　and　non-suicidal　self-injury.　The　direct　effect　of　cyberbullying　victimization　on　non-suicidal　self-injury　was　alleviated　by　strong　self-compassion.　Besides,　self-compassion　strengthened　the　direct　relation　between　cyberbullying　victimization　and　basic　psychological　needs　and　further　strengthened　the　indirect　association　of　cyberbullying　victimization　with　non-suicidal　self-injury.　Our　study　highlights　the　potential　mechanisms　underlining　the　relationship　between　cyberbullying　victimization　and　non-suicidal　self-injury,　and　it　has　important　theoretical　and　practical　implications　for　adolescent　non-suicidal　self-injury.