Extracorporeal　membrane　oxygenation　(ECMO)　is　a　life　support　system　used　in　the　treatment　of　severe　respiratory　and　circulatory　failure.　High　shear　stress　caused　by　the　high　rotational　speed　of　centrifugal　blood　pumps　can　cause　hemolysis　and　platelet　activation,　which　are　among　the　major　factors　leading　to　the　complications　of　the　ECMO　system.　In　this　study,　a　novel　blood　pump　named　rotary　displacement　blood　pump　(RDBP),　which　can　considerably　reduce　rotational　speed　and　shear　stress　while　ensuring　the　normal　pressure　flow　relationship,　was　proposed.　We　employed　computational　fluid　dynamics　(CFD)　analysis　to　investigate　the　performance　of　RDBP　under　adult　ECMO　support　operating　conditions　(5　L/min　with　350　mmHg).　The　efficiency　and　H-Q　curves　of　the　RDBP　were　calculated　to　evaluate　its　hydraulic　performance,　and　pressure,　flow　patterns,　and　shear　stress　distribution　were　analyzed　to　estimate　the　hemodynamic　characteristics　in　the　pump.　In　addition,　the　modified　index　of　hemolysis　(MIH)　was　calculated　for　the　RDBP　based　on　a　Eulerian　approach.　The　hydraulic　efficiency　of　the　RDBP　was　47.28%.　The　velocity　distribution　of　flow　field　in　the　pump　was　relatively　uniform.　Most　of　the　liquid　(more　than　75%)　in　the　pump　was　exposed　to　low　scale　shear　stress　(＜1　Pa),　which　was　close　to　normal　physiological　conditions.　The　gap　area　was　the　main　distribution　location　of　high　scale　shear　stress.　The　high　wall　shear　stress　(＞9　Pa)　volume　fraction　of　the　RDBP　was　small　and　located　in　the　boundary　areas　between　the　rotor＇s　edge　and　the　housing.　The　MIH　value　of　the　RDBP　was　9.87　+/-　0.93　(mean　+/-　SD).　The　RDBP　can　achieve　better　hydraulic　efficiency　and　hemodynamic　performance　at　lower　rotational　speed.　The　design　of　this　novel　pump　is　expected　to　provide　a　new　direction　for　developing　a　blood　pump　for　ECMO.